Results 41 to 50 of about 5,295,174 (295)

A Dynamic Study of Biochemical Self-Replication

open access: yesMathematics, 2020
As it is well understood, in biological systems, small regulatory motifs are present at all scales, thus looking at simple negative feedback loops give us some information of how autocatalytic systems may be affected by regulation.
Desire T. Gijima, Enrique Peacock-López
doaj   +1 more source

User Preferences toward Positive and Negative Feedback Information in Online Learning: Goal Achievement and Information Value Perspectives

open access: yes, 2016
We adopted 2 theoretical perspectives (goal achievement and information value) to determine the conditions under which people prefer to receive positive or negative feedback information.
Tseng, Chung-Hui
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A Negative Feedback Loop in Ultraviolet A-Induced Senescence in Human Dermal Fibroblasts Formed by SPCA1 and MAPK

open access: yesFrontiers in Cell and Developmental Biology, 2021
Secretory pathway calcium ATPase 1 (SPCA1) is a calcium pump localized specifically to the Golgi. Its effects on UVA-induced senescence have never been examined.
Hongfu Xie   +15 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Editorial: Expanding the horizon of feedback research in second language [PDF]

open access: yes, 2023
On behalf of the editorial board, we welcome readers, researchers, and potential authors to the inaugural issue of the new journal Feedback Research in Second Language. The journal aims to fill gaps in research on corrective feedback by publishing a
Deborah J. Crusan
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Negative feedback scheduling algorithm based on historical information in SDN

open access: yes网络与信息安全学报, 2018
In the current SDN architecture,the controllers suffer from lots of potential attacks.For example,malicious flow rule attacks may introduce fake flow rules to confuse the host.A negative feedback scheduling algorithm based on historical information was ...
Yingying LYU,Yunfei GUO,Zhenpeng WANG,Guozhen CHENG,Yawen WANG
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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