Results 81 to 90 of about 8,630,188 (308)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Overview of the design of the ITER heating neutral beam injectors

New Journal of Physics, 2017
The heating neutral beam injectors (HNBs) of ITER are designed to deliver 16.7 MW of 1 MeV D ^0 or 0.87 MeV H ^0 to the ITER plasma for up to 3600 s. They will be the most powerful neutral beam (NB) injectors ever, delivering higher energy NBs to the ...
R S Hemsworth, D Boilson, P Blatchford, M Dalla Palma, G Chitarin, H P L de Esch, F Geli, M Dremel, J Graceffa, D Marcuzzi, G Serianni, D Shah, M Singh, M Urbani, P Zaccaria   +14 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

100 seconds and megawatt negative ion beam accelerations at the CRAFT NNBI test facility

Nuclear Fusion
A promising negative-ion-based neutral beam injection (NNBI) system should achieve high energy, high power and long pulse simultaneously for the plasma heating and current drive in the large-scale fusion devices. A NNBI test facility has been constructed
Jianglong Wei, Yuwen Yang, Wei Liu, Yongjian Xu, Yuchen Qu, Yuming Gu, Yahong Xie, Chundong Hu, Lizhen Liang   +8 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Negative ion sources for neutral beam systems [PDF]

Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films, 1983
Neutral beams to heat the plasmas of controlled fusion experiments are generated by neutralizing the charge of positive ions after they have been focused and accelerated. The efficiency of this system decreases with ion velocity and for D+ the system is practical only at ion energies of less than about 150 keV,which is less than the energies expected ...
openaire   +3 more sources

Performance prediction of radio frequency based negative ion source using fusion neural network model

Nuclear Fusion
To accelerate the development of a radio frequency negative ion source (RF-NIS), a fusion neural network model has been developed to simulate and predict the performance of RF-NIS under set working parameters.
Yu Gu, Chundong Hu, Yang Li, Yuwen Yang, Yahong Xie, Qinglong Cui, Yuanzhe Zhao   +6 more
doaj   +1 more source

Three head men of Mer [picture]

, 1933
Part of collection: Ion Idriess glass plate negative collection.; Title based on caption in: Drums of Mer.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-vn3298393; Published in: Drums of Mer / by Ion I.

core  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Present status of numerical modeling of hydrogen negative ion source plasmas and its comparison with experiments: Japanese activities and their collaboration with experimental groups

New Journal of Physics, 2018
The present status of kinetic modeling of particle dynamics in hydrogen negative ion (H ^− ) source plasmas and their comparisons with experiments are reviewed and discussed with some new results.
A Hatayama, S Nishioka, K Nishida, S Mattei, J Lettry, K Miyamoto, T Shibata, M Onai, S Abe, S Fujita, S Yamada, A Fukano   +11 more
doaj   +1 more source