Results 51 to 60 of about 5,948,394 (284)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
A bidirectional Optimality Theoretic analysis of multiple negative indefinites in Afrikaans
Stellenbosch Papers in Linguistics, 2014 In the literature on negation, Afrikaans is generally categorised as a negative concord language. Unlike most other negative concord languages though, utterances containing multiple indefinites in the scope of negation are typically produced with a ...
Huddlestone, Kate, de Swart, Henriëtte
doaj +1 more source
Cell polarity and PIN protein positioning in Arabidopsis requie STEROL METHYLTRANSFERASE1 function [PDF]
, 2003 Plants have many polarized cell types, but relatively little is known about the mechanisms that establish polarity. The orc mutant was identified originally by defects in root patterning, and positional cloning revealed that the affected gene encodes ...
Friml, Jirí +12 more
core +2 more sources
The polarity asymmetry of negative strengthening
, 2021 The interpretation of negated antonyms is characterised by a polarity asymmetry: the negation of a positive polarity antonym (X is not interesting) is more likely to be strengthened to convey its opposite ('X is uninteresting') than the negation of a ...
Mazzarella, Diana (Prof. Dr.) +1 more
core +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Role of rac1 protein in the acquisition and mainteinance of epithelial cell polarity [PDF]
, 2009 : The acquisition of cell polarity, which includes the establishment of the tight junction barrier, the polarized assembly of the cytoskeleton and the appropriate organization of membrane traffic, requires external cues, that in epithelial cells are ...
Santoriello, Margherita
core +1 more source
Ni positivo ni negativo: una nota sobre ‘apenas’ / Neither positive nor negative: ‘a note on apenas’
Ogigia, 2015 Este trabajo se plantea un problema al que da lugar el adverbio apenas: en ciertos casos se comporta como un término negativo, mientras que en otros es positivo.
Antonio Fábregas
doaj
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source