Results 61 to 70 of about 50,406 (282)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Processing Sentences With Multiple Negations: Grammatical Structures That Are Perceived as Unacceptable

open access: yesFrontiers in Psychology, 2019
This investigation draws from research on negative polarity item (NPI) illusions in order to explore a new and interesting instance of misalignment observed for grammatical sentences containing two negative markers.
Iria de-Dios-Flores, Iria de-Dios-Flores
doaj   +1 more source

Negation in context: evidence from the visual world paradigm [PDF]

open access: yes, 2016
Literature assumes that negation is more difficult to understand than affirmation, but this might depend on the pragmatic context. The goal of this paper is to show that pragmatic knowledge modulates the unfolding processing of negation due to the ...
Moxey, Linda   +3 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Negative concord and (multiple) agree: a case study of West Flemish [PDF]

open access: yes, 2010
This paper examines the formalization of negative concord in terms of the Minimalist Program, focusing entirely on negative concord in West Flemish. It is shown that a recent analysis of negative concord which advocates Multiple Agree is empirically ...
Haegeman, Liliane, Lohndal, Terje
core   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Ni positivo ni negativo: una nota sobre ‘apenas’ / Neither positive nor negative: ‘a note on apenas’

open access: yesOgigia, 2015
Este trabajo se plantea un problema al que da lugar el adverbio apenas: en ciertos casos se comporta como un término negativo, mientras que en otros es positivo.
Antonio Fábregas
doaj  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

TIPOS DE NEGAÇÃO

open access: yesCadernos de Estudos Lingüísticos, 2011
The aim of this paper is to investigate negation in (Brazilian) Portuguese. There are two general types of negation: one that operates over the matrix sentence and another one which is non-sentential.
Carlos Mioto
doaj   +1 more source

The Effect of Negators, Modals, and Degree Adverbs on Sentiment Composition

open access: yes, 2016
Negators, modals, and degree adverbs can significantly affect the sentiment of the words they modify. Often, their impact is modeled with simple heuristics; although, recent work has shown that such heuristics do not capture the true sentiment of multi ...
Kiritchenko, Svetlana, Mohammad, Saif M.
core   +1 more source

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