Results 41 to 50 of about 8,358,165 (249)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Open Versus Closed Negative Pressure Wound Therapy For Contaminated and Dirty Surgical Wounds: A Quasi-Experimental Study

Pakistan Armed Forces Medical Journal
Objectives: To determine the efficacy of open versus closed negative pressure wound therapy for contaminated and dirty surgical wounds in terms of time duration to full wound healing. Study Design: Quasi-experimental study.
Saqib Hameed, Mubashir Hanif, Zaki Hussain Salamat, Sohail Ilyas, Omar Farooq, Shafqat Rehman   +5 more
doaj   +1 more source

Effectiveness of Health Education Program on Negative Pressure Wound Therapy for Patients with Limb Wounds [PDF]

Helwan International Journal for Nursing Research and Practice
Background: Negative Pressure Wound Therapy, is a treatment that uses a sealed dressing and a suction pump to help wounds heal used for wounds difficult to heal, the patient used it at outpatient clinic. Aim: this study aimed to evaluate health education
Mayada Mahmoud Sabea, Rasha Ahmed, Fatma Eiz-Elregal   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Negative pressure wound therapy of an anal cancer to facilitate further treatment – case report. [PDF]

, 2016
A common treatment of bad healing wounds is vacuum assisted therapy (negative pressure wound therapy). The main clinical goal are: reduced time of wound healing, decreasing frequency of septic complications, and better functional and cosmetic effect. One
Banasiewicz, Tomasz, Błażejewska, Dorota, Kicińska, Magdalena   +2 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Negative Pressure Wound Therapy in Lower Limb Reconstruction

Pakistan Armed Forces Medical Journal
Objective: To access the efficacy of negative pressure wound therapy and, its potential outcomes in lower limb reconstruction. Study Design: Prospective observational study.
Afia Ayub, Shahid Hameed Choudhary, Abdul Majid, Palwasha Mansoor, Muhammad Umer Qureshi, Shah Faisal   +5 more
doaj   +1 more source

Instillation-TIME (iTIME) as a rationale amendment for TIME conception. Is there enough evidence for the efficiency of negative pressure wound therapy with instillation (iNPWT) to announce a breakthrough idea for wound treatment? [PDF]

, 2019
An increased number of patients developing difficult-to-heal wounds results in billions spending for chronic wound care management. Introduction of TIME conception has been a breakthrough idea for wound healing based on phase-adapted wound therapy that ...
Drews, Michał, Banasiewicz, Tomasz, Bobkiewicz, Adam, Studniarek, Adam, Krokowicz, Łukasz   +4 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Negative-pressure Wound Therapy for Periocular Necrotizing Fasciitis

Plastic and Reconstructive Surgery, Global Open, 2018
Summary:. Periocular necrotizing fasciitis is a rare, but potentially blinding, or even fatal disease. The authors report a case of a 44-year-old man who presented with quiescent bilateral periocular and facial necrotizing fasciitis.
John W. Gillespie, III, MD, Jui K. Pandya, MD, Shilpa M. Agarwal, MD, Andrew A. Gassman, MD, Mark Krakauer, MD, MPhil   +4 more
doaj   +1 more source