Results 51 to 60 of about 8,358,165 (249)

The modulation of the burn wound environment by negative pressure wound therapy: Insights from the proteome

open access: yes, 2020
Negative pressure wound therapy has been used to promote wound healing in a variety of settings, including as an adjunct to silver‐impregnated dressings in the acute management of paediatric burns.
Griffin, BR   +6 more
core   +1 more source

Modern alternative or first-line treatment: How to safely use Negative Pressure Wound Therapy in Diabetic Foot Syndrome? [PDF]

open access: yes, 2015
Clinical experience and basic science studies show that Negative Pressure Wound Therapy (NPWT) is a promising yet still under-used treatment method for patients with diabetic foot syndrome (DFS).
Mrozikiewicz-Rakowska, Beata   +5 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Negative pressure wound therapy in patients with diabetic foot

open access: yesActa Orthopaedica et Traumatologica Turcica, 2020
Objective: In this study our aim was to compare the results of standard dressing treatment to negative pressure wound therapy (NPWT) performed with a vacuum-assisted closure (VAC) device in patients with diabetic foot ulcers. \r\nMethods: We assessed the
Ali Engin Ulusal   +4 more
doaj   +1 more source

Negative Pressure Wound Therapy for Necrotizing Fasciitis and Compartment Syndrome of the Upper Extremity — a case report [PDF]

open access: yes, 2019
Background: Necrotizing fasciitis (NF) is a lifethreateninginfection of the subcutaneous tissues that spreadsalong the underlying fascia. Despite the early and aggressivesurgical fasciotomy and necrectomy, its mortality rate is stillhigh.
Szentkereszty, Zsolt   +6 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Clinical and cost-effectiveness of negative pressure wound therapy versus usual care for surgical wounds healing by secondary intention: the SWHSI 2 pragmatic RCT

open access: yesHealth Technology Assessment
Background Surgical wounds healing by secondary intention occur if a surgical wound is not closed or dehisces following primary closure. Surgical wounds healing by secondary intention are common and adversely affect patients’ quality of life.
Catherine Arundel   +23 more
doaj   +1 more source

Negative pressure wound therapy in the treatment of surgical site infection in cardiac surgery [PDF]

open access: yesRevista Brasileira de Enfermagem
Objectives: to describe the relationship between epidemiological and clinical characteristics of postoperative cardiac surgery patients undergoing negative pressure wound therapy for the treatment of surgical site infection.
Mayra de Castro Oliveira   +3 more
doaj   +4 more sources

Endoluminal negative pressure wound treatment of anastomotic leakage in rectal surgery patients – critical review of the literature. [PDF]

open access: yes, 2015
During past 20 years the use of negative pressure wound therapy (NPWT) has shown it effectivity and efficiency in treatment of different indications.
Daniela Karasová, Huľo, Edward
core   +1 more source

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