Results 61 to 70 of about 161,210 (295)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Combined negative pressure wound therapy with irrigation and dwell time and artificial dermis prevents infection and promotes granulation formation in a ruptured giant omphalocele: a case report

BMC Pediatrics, 2022
Background Omphalocele is a congenital abdominal wall defect of the umbilical cord insertion site. A giant omphalocele, with a fascial defect > 5 cm in diameter and/or containing > 50% of the liver within the hernia sac, can be challenging for pediatric ...
Yoichi Nakagawa, Hiroo Uchida, Akinari Hinoki, Chiyoe Shirota, Wataru Sumida, Satoshi Makita, Hizuru Amano, Masamune Okamoto, Aitaro Takimoto, Seiya Ogata, Shunya Takada, Daiki Kato, Yousuke Gohda   +12 more
doaj   +1 more source

Evaluation of the Healing Progress of Pressure Ulcers Treated with Cathodal High-Voltage Monophasic Pulsed Current: Results of a Prospective, Double-blind, Randomized Clinical Trial [PDF]

, 2016
OBJECTIVE: To investigate the effectiveness of high-voltage monophasic pulsed current (HVMPC) as an adjunct to a standard wound care for the treatment of Stage II and III pressure ulcers (PrUs).
Agnieszka Nawrat-Szoltysik, Andrzej Franek, Anna Polak, Anna Walczak, Cezary Kucio, Edward Blaszczak, Jakub Taradaj, Lidia Bialek, Luther C. Kloth, Malgorzata Paczula   +9 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Negative pressure wound therapy for complex oral wounds

Journal of Surgical Case Reports, 2023
Abstract Negative pressure wound therapy provides a nonsurgical treatment option for many types of complex wounds. This therapy utilizes the vacuum-assisted closure device, which decreases air pressure, removes fluid that accumulates within the wound, and aids to facilitate changes that promote healing.
Mykaihla Sternick, James C Gates, Allen Champion, Andrew Yampolsky   +3 more
openaire   +3 more sources

A case report of cutaneous mucormycosis of the hand after minor trauma in a patient with acute myeloid leukaemia [PDF]

, 2019
Background: Mucormycosis is a rare but life-threatening infection, caused by fungi of the Mucorales order, which can be found in soil, rotting leaves or on animals. Through characteristic angioinvasive growth, infections with mucor spores can occur as a
Maleitzke, Tazio, Märdian, Sven, Stahnke, Katharina, Trampuz, Andrej   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

An Affordable Custom-Built Negative Pressure Wound Therapy

The Annals of African Surgery, 2017
Negative pressure wound therapy (NPWT) is a well-established and effective method for treating complex wounds. However, this modality of treatment may not be available in limited-resource countries due to the high cost.
Alshazaly Mohamed Abdal-Kareem Isaac, Mohamed Elamin Salim, Ihab Abdel-Rahim Mohamed Ahmed   +2 more
doaj  

Hoitohenkilökunnan ammatilliset valmiudet haavan alipaineimuhoidon toteutukseen perusterveydenhuollossa [PDF]

, 2014
Tämän opinnäytetyön tarkoituksena oli kuvata perusterveydenhuollon hoitohenkilökunnan ammatillisia valmiuksia haavan alipaineimuhoidon toteutukseen.
Hintikka, Jouni, Ruuskanen, Jani
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source