A genetic and economic evaluation of lactose in the New Zealand dairy industry : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Animal Science [PDF]
, 2016 Milk composition in New Zealand is heavily influenced by the selection for Breeding Worth (BW) and the breed composition of the national herd. Under selection for BW a greater emphasis is placed upon protein (39% of emphasis) than fat yield (13% of ...
Sneddon, Nicholas William
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Evolutionary Selection of Expectations in Positive and Negative Feedback Markets [PDF]
An economic environment is a feedback system, where dynamics of aggregate variables depend on individual expectations and also shape them. The type of feedback mechanism is crucial for the aggregate outcome.
Anufriev, M., Hommes, C.H., Philipse, R.
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Ethnic enclaves and immigrant labour market outcomes: quasi-experimental evidence [PDF]
, 2006 This study investigates empirically how residence in ethnic enclaves affects labour market outcomes of refugees. Self-selection into ethnic enclaves in terms of unobservable characteristics is taken into account by exploitation of a Danish spatial ...
Piil Damm, A.
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Does Private Tutoring Payoff? [PDF]
We assess the causal effect of private tutoring on the probability of university placement in Turkey. We find that tutoring increases the probability of being placed in a university when non-random selection is ignored.
Gurun, Ayfer, Millimet, Daniel L.
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Negative frequency-dependent selection is frequently confounding [PDF]
Frontiers in Ecology and Evolution, 2017 AbstractThis preprint has been reviewed and recommended by Peer Community in Evolutionary Biology (http://dx.doi.org/10.24072/pci.evolbiol.100024).The existence of persistent genetic variation within natural populations presents an evolutionary problem as natural selection and genetic drift tend to erode genetic diversity. Models of balancing selection
openaire +3 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The contribution of chemokines and migration to the induction of central tolerance in the thymus
Frontiers in Immunology, 2015 As T cells develop, they migrate throughout the thymus where they undergo essential bi-directional signaling with stromal cells in distinct thymic microenvironments. Immature thymocyte progenitors are located in the thymic cortex.
Zicheng eHu +2 more
doaj +1 more source