Results 101 to 110 of about 3,805,307 (284)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The negative sequence impedance as fault indicator in induction motors

Revista Facultad de Ingeniería Universidad de Antioquia, 2010
En este trabajo se presenta un algoritmo basado en la impedancia de secuencia negativa para detectar fallas entre espiras de los motores de inducción, se explica su implementación en un prototipo electrónico de diagnóstico y sus resultados se verifican ...
Fernando Villada, Diego Raúl Cadavid, José Edinson Aedo, Bernardo Andrés Benavides, Esteban Velilla   +4 more
doaj  

SOME EXACT LIMIT THEOREMS FOR NEGATIVELY ASSOCIATED SEQUENCES

Kyushu Journal of Mathematics, 2013
Let \(\alpha ,\delta >0\) and \(L=\delta ^{-1}\operatorname{E}\left| N\right|^{\alpha \delta +2},\) where \(N\) stands for a standard normal random variable. Let also \(w_{n}=(\log \log n)^{\delta -1}/n^{2}\log n,\) \(n\geq 3\). Let \(X_{1},X_{2},\dots\) be a stationary sequence of negatively associated random variables with \(\operatorname{E}X_{1}=0\),
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sequence Matters: an Experimental Study of the Effects of Experiencing Positive and Negative Reciprocity [PDF]

This paper presents an experimental analysis of people’s behavior in situations involving both positive and negative reciprocity. The experiment implements sequences of two types of extensive form games called Punishment games and Trust games.
Giorgio Coricelli
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Research of STATCOM control strategy under underground unbalanced conditio

Gong-kuang zidonghua, 2013
For problem that underground unbalanced condition will result in poor control performance of STATCOM, affecting compensation effect, the paper proposed a control strategy adopting improved switch function method and negative sequence voltage feedforward,
TANG Xia, PENG Zhi-yu, WANG Sha-sha, HAN Li   +3 more
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Characteristics and Control Strategy of Cascaded SVG with Star-configuration Considering Negative-sequence Compensation

Kongzhi Yu Xinxi Jishu, 2013
This paper illustrated var and negative sequence comprehensive compensation principles of cascaded static var generator(SVG) with star-configuration. The mathematical expression of zero-sequence voltage was deduced, and subsequently zero-sequence voltage
XIONG Qiaopo, LUO An, ZENG Zhizhen
doaj