Results 91 to 100 of about 1,650,409 (264)

Characteristics and Control Strategy of Cascaded SVG with Star-configuration Considering Negative-sequence Compensation

open access: yesKongzhi Yu Xinxi Jishu, 2013
This paper illustrated var and negative sequence comprehensive compensation principles of cascaded static var generator(SVG) with star-configuration. The mathematical expression of zero-sequence voltage was deduced, and subsequently zero-sequence voltage
XIONG Qiaopo, LUO An, ZENG Zhizhen
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Analysis and Compensation of Negative Phase-sequence for Traction Transformer

open access: yesKongzhi Yu Xinxi Jishu, 2014
It analyzed the characteristics of negative phase-sequence current for traction transformers with different connection types under different loads. The three-phase current asymmetry degree of traction transformers is serious under both traction load and ...
SHI Minghui   +3 more
doaj  

Asymmetric fault voltage support scheme for soft open points based on improved negative sequence voltage outer loop

open access: yes电力工程技术
Flexible interconnection and dynamic power flow regulation in distribution networks are achieved by soft open point (SOP), optimizing the configuration and scheduling of distribution resources. To improve the load voltage during asymmetric ground faults,
Xuze WANG, Wu CHEN, Haixi ZHAO, Shi CHEN
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Chaotic sequence based polar code encrypted scheme in negative secrecy capacity case

open access: yesTongxin xuebao, 2020
A chaos based encrypted polar coding scheme,which could be applied to the negative secrecy capacity case,was proposed.Chaotic sequences were employed to encrypt the information bits and fill the frozen bits.And multi-block polar coding structure was also
Xiaohui ZHANG, Shunliang ZHANG, Bowen LI
doaj   +2 more sources

Fault Location Method for Distribution Network with Photovoltaic Power Based on Negative Sequence Component

open access: yesZhongguo dianli
In order to solve the problem that the fault current can not correctly indicate the fault section due to the connection of photovoltaic power to the distribution network, the three-sequence component of the faulty distribution network with photovoltaic ...
Manlin HU   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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