Results 91 to 100 of about 6,698,062 (304)

Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B

, 2004
BACKGROUND: Available treatments for hepatitis B e antigen (HBeAg)-negative chronic hepatitis B are associated with poor sustained responses. As a result, nucleoside and nucleotide analogues are typically continued indefinitely, a strategy ...
PEGINTERFERON ALFA A. HBEAG NEGATIVE CHRONIC HEPATITIS B. STUDY GROUP, MARCELLIN P, BONINO, FERRUCCIO, LAU GK   +3 more
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Identification and location method of asymmetric faults in coal mine power network

Gong-kuang zidonghua, 2018
Three asymmetrical faults of singe-phase grounding, singe-phase line breakage and ferroresonance in coal mine power network are easily misjudged, and existing methods hardly identify the three faults correctly.
WANG Qingliang, QIN Jie, LIU Xinru
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

MOSAL : software tools for multiobjective sequence alignment [PDF]

, 2014
Multiobjective sequence alignment brings the advantage of providing a set of alignments that represent the trade-off between performing insertion/deletions and matching symbols from both sequences. Each of these alignments provide a potential explanation
Monsanto Pinheiro, Miguel, Maryam Abbasi, Luís LuísPaquete, Paquete, Luís, Pedro Matias, Luís Paquete, Abbasi, Maryam, Miguel Pinheiro, Matias, Pedro   +8 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Negative Pressure Wound Therapy (NPWT) in Breast Surgery [PDF]

, 2019
Background: The use of Negative Pressure Wound Dressing has been found to promote the wound healing process, therefore, reducing the risk of surgical site complications. The use of this technique amongst breast cancer patients, who have often encountered
Harsten, Rebecca, SALIH, Vanessa, Asaad, Amira, Banasiewicz, Tomasz, SAAD ABDALLA AL-ZAWI, Abdalla, Alkhir, Momen Abdou, BenRafe, Hamad   +6 more
core   +1 more source

A Software-decoding Algorithm of Resolver Based on the Separation of Positive and Negative Sequence

Kongzhi Yu Xinxi Jishu, 2021
In order to eliminate the angle error caused by amplitude imbalance and phase non-orthogonality of resolver sine and cosine feedback signals, dq transform and positive and negative sequence separation are carried out to resolve sine and cosine feedback ...
GUO Zhida, CHEN Lei, ZHOU Cheng, CHEN Jianming, LIU Wang   +4 more
doaj  

Fibonacci and Lucas sequences at negative indices

, 2014
This study investigate the Fibonacci and Lucas sequences at neg- ative indices. In this paper we give the formulas of F????(nk+r) and L????(nk+r) depending on whether the indices are odd or even. For this purpose we con- sider a special matrix and we give various combinatorial identities related with the Fibonacci and Lucas sequences by using the ...
Halıcı, Serpil, Akyüz, Zeynep
openaire   +3 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source