Results 71 to 80 of about 6,698,062 (304)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Differential expression analysis for sequence count data [PDF]

, 2010
*Motivation:* High-throughput nucleotide sequencing provides quantitative readouts in assays for RNA expression (RNA-Seq), protein-DNA binding (ChIP-Seq) or cell counting (barcode sequencing).
Simon Anders, Wolfgang Huber, Klawonn, Frank   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Increased performance uncertainty in children with ADHD? - Elevated post-imperative negative variation (PINV) over the ventrolateral prefrontal cortex [PDF]

, 2011
Background: We aimed to investigate the influences of attention deficit/hyperactivity disorder (ADHD) on response evaluation, as reflected by the postimperative negative variation (PINV), a slow event-related potential.
Werner, Janina, Resch, Franz, Weisbrod Matthias, Stephan Bender, Rößner, Veit, Matthias Weisbrod, Veit Roessner, Werner Janina, Bender Stephan, Roessner, Veit, Franz Resch, Roessner Veit, Bender, Stephan, Resch Franz, Weisbrod, Matthias, Janina Werner   +15 more
core   +1 more source

A Negative Sequence Impedance Design and Regulation Strategy for Negative Sequence Current Sharing Among Grid-Forming Sources in Microgrids Considering Topology Impacts

IEEE Open Journal of Power Electronics
The accurate control of negative sequence (NS) current distribution among multiple grid-forming (GFM) sources can lower the requirement on NS current capability of the sources.
Dingrui Li, Chengwen Zhang, Zhihao Jiang, Yu Su, Yiwei Ma, Fred Wang, Leon M. Tolbert   +6 more
doaj   +1 more source

Microprocessor-based negative-sequence relay

International Journal of Electrical Power & Energy Systems, 1986
Abstract A three-phase power system can be subjected to various types of faults. Symmetrical components furnish a tool which is well suited for analysing such faults. This paper describes a microprocessor-based system which calculates the symmetrical components from the sampled data of the three phase quantities in real time. The computed symmetrical
S.I. Ahson, J. Henry, D.S. Rundhay
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Adaptive negative-sequence fault-component directional relay for two-terminal weak-feed AC systems based on negative-sequence impedance reconstruction control

International Journal of Electrical Power & Energy Systems
The two-terminal weak-feed AC system (TW-AC system) integrated with large-scale photovoltaic (PV) plants via voltage-source-converter-based high-voltage direct current (VSC-HVDC) exhibits distinct weak-infeed characteristics at both terminals, where ...
Junjie Hou, Changjian Zhang, Yanfang Fan, Guobing Song, Xiaofang Wu   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Sequence-Rating task results.

, 2019
Panel A shows the results for each participant, with the vertical axis the SR score (i.e., from the best-fit line of the sequence-rating dependent measure across the tested sequences).
Jaeseung Jeong (220472), Jaehyung Kwon (7465205), Sangsup Yoon (7465199), Jerald D. Kralik (7039958), Sewoong Lim (7465202)   +4 more
core   +1 more source