Results 61 to 70 of about 3,805,307 (284)

The impact of different negative training data on regulatory sequence predictions.

PLoS ONE, 2020
Regulatory regions, like promoters and enhancers, cover an estimated 5-15% of the human genome. Changes to these sequences are thought to underlie much of human phenotypic variation and a substantial proportion of genetic causes of disease.
Louisa-Marie Krützfeldt, Max Schubach, Martin Kircher   +2 more
doaj   +1 more source

Irregular Input Data in Convergence Acceleration and Summation Processes: General Considerations and Some Special Gaussian Hypergeometric Series as Model Problems

, 2000
Sequence transformations accomplish an acceleration of convergence or a summation in the case of divergence by detecting and utilizing regularities of the elements of the sequence to be transformed.
Abramowitz, Aitken, Baker, Bender, Bender, Bender, Bhattacharya, Bhowmick, Brezinski, Brezinski, Brezinski, Brezinski, Brezinski, Brezinski, Carlson, Cioslowski, Delahaye, Erdélyi, Ernst Joachim Weniger, Forrey, Gander, Grotendorst, Guttmann, Homeier, Jentschura, Jentschura, Knopp, Levin, Liem, Marchuk, Roy, Roy, Sablonniere, Sablonniere, Sablonniere, Sablonniere, Sarkar, Seaborn, Sidi, Sidi, Simon, Skála, Skála, Slater, Smith, Smith, Spanier, Steinborn, Temme, Vinette, Wang, Weniger, Weniger, Weniger, Weniger, Weniger, Weniger, Weniger, Weniger, Weniger, Weniger, Weniger, Weniger, Weniger, Weniger, Weniger, Weniger, Weniger, Weniger, Wimp, Wynn, Wynn, Čížek   +72 more
core   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Hausdorff moment sequences induced by rational functions

, 2019
We study the Hausdorff moment problem for a class of sequences, namely $(r(n))_{n\in\mathbb Z_+},$ where $r$ is a rational function in the complex plane. We obtain a necessary condition for such sequence to be a Hausdorff moment sequence.
Reza, Md. Ramiz, Zhang, Genkai
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Microprocessor-based negative-sequence relay

International Journal of Electrical Power & Energy Systems, 1986
Abstract A three-phase power system can be subjected to various types of faults. Symmetrical components furnish a tool which is well suited for analysing such faults. This paper describes a microprocessor-based system which calculates the symmetrical components from the sampled data of the three phase quantities in real time. The computed symmetrical
S.I. Ahson, J. Henry, D.S. Rundhay
openaire   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source