Results 101 to 110 of about 2,400,147 (293)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Algorithm of Equivalent Inter-phase Impedance for Three-phase Unbalanced Loads and Its Applications

Kongzhi Yu Xinxi Jishu, 2015
It presented a method for calculating equivalent inter-phase impedance of three-phase unbalanced loads in three-phase three-wire system. Phase voltages and line currents of unbalanced system were decomposed into positive sequence and negative sequence ...
ZHU Mingxing, SUN He, GUAN Shenlong, HU Maoliang, JIAO Yadong   +4 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Hybrid voltage and current control strategy for virtual synchronous generator under unbalanced voltage conditions

IET Renewable Power Generation
The traditional VSG strategy does not consider the negative sequence component, which will lead to current imbalance and power oscillation under unbalanced voltage.
Yichao Wang, Dongrong Wang, Zuliang Huang, Yan Li   +3 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Collaborative Suppression Strategy for AC Asymmetric Faults in Offshore Wind Power MMC-HVDC Systems

Energies
When offshore wind power is connected to a grid via Modular multilevel converter-based High Voltage Direct Current (MMC-HVDC), the sending-end alternating current (AC) system is susceptible to asymmetrical faults. These faults lead to overcurrent surges,
Xiang Lu, Chenglin Ren, Shi Jiao, Jie Shi, Weicheng Li, Hailin Li   +5 more
doaj   +1 more source

Compensation of negative sequence stator flux of doubly-fed induction generator using polar voltage control-based direct torque control under unbalanced grid voltage condition

The Journal of Engineering, 2015
This study proposes a polar voltage control-based direct torque control method to reduce the effects of unbalanced grid voltage on doubly-fed induction generator (DFIG)-based wind turbine system.
Badrinarayan Bansilal Pimple, Vishal Yashwant Vekhande, Baylon G. Fernandes   +2 more
doaj   +1 more source

The Plasma Interaction Experiment (PIX) description and test program [PDF]

The plasma interaction experiment (PIX) is a battery powered preprogrammed auxiliary payload on the LANDSAT-C launch. This experiment is part of a larger program to investigate space plasma interactions with spacecraft surfaces and components.
Culp, D. H., Domino, E. J., Haley, F. A., Ignaczak, L. R., Shaker, F. J.   +4 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source