Results 81 to 90 of about 868,690 (284)
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The open-phase operation of the AC connection line connecting the wind farm and MMC generates negative sequence current in the system, which cause the overcurrent, overvoltage, power fluctuation and other problems.
Botong Li +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Negative sequence of the turbogenerator stator current
Presented article contains the simulation results of the turbogenerator negative sequence reactance and resistance. The results were obtained by using field-circuit model of the turbogenerator.
Gozdowiak, A., Kisielewski, P.
core
Analysis the wiring of head and tail pully driving & bidirectional 6KV motor,and found the reason of negative phase sequence over current protection malfunction did occur when the motor ran in the reverse direction , then compared the solution ...
Rong Chun Yang +2 more
core +1 more source
Dominant-Negative Proteins in Herpesviruses - From Assigning Gene Function to Intracellular Immunization [PDF]
Investigating and assigning gene functions of herpesviruses is a process, which profits from consistent technical innovation. Cloning of bacterial artificial chromosomes encoding herpesvirus genomes permits nearly unlimited possibilities in the ...
Christian A. Mohr +9 more
core +1 more source
Reassessment of Permissible Negative Sequence Current for Power Plant Operation of Taipower
The N3 power plant of Taipower is located in the southern tip of Taiwan and connected to the power pool by four out-linking 345-kV overhead transmission circuits. There are two 951-MW generators. Each generator occupied 11% of the system peak load in 1985 when the generator was in commercial operation.
Ping-heng Ho +3 more
openaire +2 more sources
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

