Results 81 to 90 of about 12,500,295 (288)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A Control Method for Unbalanced Current in Grid Type Energy Storage Based on Negative Sequence Virtual Impedance

IEEE Open Journal of Circuits and Systems
Grid type energy storage has inertia support capability, and unbalanced grid voltage will cause grid type energy storage current fluctuation and active power fluctuation.
Li You, Liangli Xiong, Gang Han, Sheng Zhang, Zhijian Fang   +4 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

W-Loss Recensioni Negative - Non riesci a perdere peso?

, 2022
W-Loss Recensioni Negative è un noto e importante integratore dimagrante studiato per aiutarti a perdere peso. Il miglioramento è realizzato con un mix estremo di rimozioni originali e intonacature clinicamente dimostrate.
W-Loss Recensioni Negative
core   +1 more source

Investigation on Stator Winding Inter-turns Short Circuit Fault Diagnosis

Journal of Harbin University of Science and Technology, 2018
On the basis of negative sequence current generation mechanism analysis of synchronous generator stator winding inter-turns short circuit，the method of detecting and diagnosing synchronous generator stator winding inter-turns short circuit is proposed ...
ZHAO Hong-sen, GE Bao-jun, TAO Da-jun, YANG Kun, XING Guang   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Sequence-Specific Self-Assembly of Positive and Negative Monomers with Cucurbit[8]uril Linkers

, 2018
The self-assembly into dynamic oligomers of Cucurbit[8]­uril (CB[8]), a positive ditopic Ir­(III) bis-terpyridine complex, and a negative ditopic Fe­(II) bis-terpyridine complex flanked by four butyrate side chains was assessed to answer a seemingly ...
Eric Masson (611798), Ian del Valle (4871839), Kondalarao Kotturi (4871836), Jan Schulz (2497219), Mersad Raeisi (4871830), Paulina Dornblut (4871833)   +5 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source