Results 81 to 90 of about 868,638 (260)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
International Transactions on Electrical Energy SystemsIn view of the fact that the influence of positive and negative sequence decomposition, which is widely used in positive and negative sequence decoupling control in control system, on the fault current calculation process is not deeply considered in the ...
Botong Li +4 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Control strategy for microgrid under three-phase unbalance condition
Journal of Modern Power Systems and Clean Energy, 2016 Microgrid (MG) is generally developed at utility terminal which contains lots of unbalanced loads and distributed generations (DGs). The interaction between MG and the unbalance loads or DGs will degrades the control performance of interfaced inverter in
Hongtao Shi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Kongzhi Yu Xinxi Jishu, 2013 This paper illustrated var and negative sequence comprehensive compensation principles of cascaded static var generator(SVG) with star-configuration. The mathematical expression of zero-sequence voltage was deduced, and subsequently zero-sequence voltage
XIONG Qiaopo, LUO An, ZENG Zhizhen
doaj
电力工程技术Flexible interconnection and dynamic power flow regulation in distribution networks are achieved by soft open point (SOP), optimizing the configuration and scheduling of distribution resources. To improve the load voltage during asymmetric ground faults,
Xuze WANG, Wu CHEN, Haixi ZHAO, Shi CHEN
doaj +1 more source