Results 61 to 70 of about 12,500,295 (288)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Effects of Negative Sequence Voltage Subharmonics on Cage Induction Motors

open access: yes, 2022
In some power systems, voltage waveforms contain, apart from harmonics, interharmonics and subharmonics that are components of frequency less than or not an integer multiple of the fundamental frequency.
Marcin Pepliński   +4 more
core   +1 more source

Development and Application of Power Quality Comprehensive Control Equipment with Active Power Transfer

open access: yesKongzhi Yu Xinxi Jishu, 2015
Power quality problems of negative sequence current, voltage fluctuation and low power factor in traction power supply system are caused by the high-speed electric railway’s unique power mode and complex operating conditions of electric locomotives ...
GONG Fen   +3 more
doaj  

Implementation of Current Harmonic Suppression for Imbalance in Six-Phase Permanent Magnet Synchronous Motor Drives

open access: yesEnergies
Current harmonics in six-phase permanent magnet synchronous motors (PMSMs) arise from inherent asymmetries caused by manufacturing tolerances and nonlinear characteristics in the inverter output. Additionally, magnetic saturation and slight imbalances in
Yu-Ting Lin   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Induction of Zero-Phase-Sequence Voltage by Negative-Phase-Sequence Current in a Synchronous Generator.

open access: yesIEEJ Transactions on Industry Applications, 1993
The induction of zero-phase-sequence voltage by negative-phase-sequence current in a salient pole synchronous generator is proved experimentally and theoretically. In the method of symmetrical coordinates, it has been believed that positive-, negative- and zero-phase-sequence components are independent. But an experiment driving a synchronous generator
Takase, Fuyuto   +4 more
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Effects of DC-Current for Short-Time Negative Sequence Current of Synchronous Machine

open access: yesIEEJ Transactions on Industry Applications, 2001
When a line-to-lire short-circuit occurs, the positive-sequence-, the negative-sequence-and the DC-current flow in the armature winding of synchronous machine. The negative-sequence current is limited in JEC-114, as this current causes the induced current and the overheat on the surface of the rotor.
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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