Results 101 to 110 of about 2,776,258 (309)

First-episode psychosis in treatment-resistant schizophrenia: a cross-sectional study of a long-term follow-up cohort

open access: yesBMC Psychiatry, 2018
Background Approximately one-third of schizophrenia patients eventually develop treatment-resistant schizophrenia (TRS). Although the time course of TRS development varies from patient to patient, the details of these variations have not been clarified ...
Nobuhisa Kanahara   +4 more
doaj   +1 more source

Are lay people good at recognising the symptoms of schizophrenia? [PDF]

open access: yes, 2013
©2013 Erritty, Wydell. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
AF Jorm   +35 more
core   +2 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Dealing with schizophrenia in general practice

open access: yesSouth African Family Practice, 2012
Schizophrenia is a psychiatric illness of unknown aetiology, and impairs cognition and social and occupational functioning. It is challenging in terms of the disability it causes, the unclear nature of what causes it, the complexity of diagnosis and ...
N. Khamker
doaj   +1 more source

Thrombolytics in Pediatric Stroke: Imaging Modalities [PDF]

open access: yes, 2020
Thrombolytics in Pediatric Stroke: Imaging Modalities Katherine Au, Dept. of Biomedical Engineering, with Dr. Bisi Hollist, Inova Neuroscience and Spine Institute We report the potential danger associated with an initial neuroimaging-negative cerebral ...
Au, Katherine, Hollist, Bisi
core   +1 more source

Coping with Positive and Negative Symptoms of Schizophrenia [PDF]

open access: yes, 2010
Objective: Although coping with positive symptoms of schizophrenia has been studied widely, few studies have examined coping with negative symptoms.
Bond, Gary R.   +4 more
core   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim   +3 more
wiley   +1 more source

Serum levels of S100B in patients with chronic schizophrenia during treatment augmentation with sarcosine: results of the double-blind, randomized, placebo-controlled PULSAR study

open access: yesFrontiers in Pharmacology
IntroductionSarcosine (N-methylglycine) normalizes glutamatergic neurotransmission in schizophrenia and ameliorates primary negative symptoms. This amino acid may also directly or indirectly influence glial function and therefore levels of S100B, calcium-
Agnieszka Pawlak   +2 more
doaj   +1 more source

The bargaining model of depression [PDF]

open access: yes, 2002
Minor depression—low mood often accompanied by a loss of motivation—is almost certainly an adaptation to circumstances that, in ancestral environments, imposed a fitness cost. It is, in other words, the psychic equivalent of physical pain.
Hagen, Edward H
core  

Attachment-related expectations and mother-referent memory bias in middle childhood [PDF]

open access: yes, 2014
Understanding the cognitive processing of attachment-relevant information has become a major focus of attachment research. Previous research demonstrated links between attachment and memory for attachment-related information, but results were ...
Bosmans, Guy   +3 more
core   +1 more source

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