Results 81 to 90 of about 1,691,473 (292)

The Effectiveness of Humor Skills Training on Positive and Negative Symptoms of Chronic Schizophrenia Spectrum

Journal of Holistic Nursing and Midwifery, 2019
Introduction: Although humor plays an important role in improving people s mental and physical health, empirical studies on the effectiveness of humor skills training to improve the symptoms of the patients with schizophrenia are scarce.
Akbar Atadokht, Sorayya Ebrahimzadeh, Niloofar Mikaeeli   +2 more
doaj  

Negative Symptoms and Emotions in Schizophrenia [PDF]

Schizophrenia Bulletin, 1989
A 32-year-old man, who has suffered from schizophrenia for 12 years, has been rated by five professionals using the Scale for the Assessment of Negative Symptoms. These ratings are compared with samples of the patient's writing, which reflect his emotions.
openaire   +2 more sources

Revisiting the therapeutic effect of rTMS on negative symptoms in schizophrenia: A meta-analysis [PDF]

, 2014
This study sought to determine the moderators in the treatment effect of repetitive transcranial magnetic stimulation (rTMS) on negative symptoms in schizophrenia. We performed a meta-analysis of prospective studies on the therapeutic application of rTMS
Yu, Xin, Shi, Chuan, Chan, Raymond C. K., Shum, David H. K., Cheung, Eric F. C.   +4 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

The Brief Core Schema Scales (BCSS): psychometric properties and associations with paranoia and grandiosity in non-clinical and psychosis samples [PDF]

, 2006
Background. Traditional instruments that measure self-esteem may not relate directly to the schema construct as outlined in recent cognitive models. The Brief Core Schema Scales (BCSS) aim to provide a theoretically coherent self-report assessment of ...
Smith, Ben, Dunn, Graham, Hodgekins, J, Smith, B, Freeman, D, Gracie, A, Fowler, D, Kuipers, E, Bebbington, Paul, Coker, Sian, Garety, P, Dunn, G, Bashforth, H, Coker, S, Fowler, David, Garety, Philippa, Freeman, Daniel, Gracie, Alison, Bebbington, P, Hodgekins, Joanne, Garety, P; id_orcid, Bashforth, Hannah, Kuipers, E; id_orcid, Kuipers, Elizabeth   +23 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Effect of Aerobic Exercise on Improving Symptoms of Individuals With Schizophrenia: A Single Blinded Randomized Control Study

Frontiers in Psychiatry, 2018
Introduction: Antipsychotic treatment can improve the symptoms of schizophrenia; however, residual symptoms after antipsychotic treatment are frequent.
Peng-Wei Wang, Peng-Wei Wang, Huang-Chi Lin, Huang-Chi Lin, Chwen-Yng Su, Ming-De Chen, Kuo C. Lin, Chih-Hung Ko, Chih-Hung Ko, Chih-Hung Ko, Cheng-Fang Yen, Cheng-Fang Yen   +11 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

First-episode psychosis in treatment-resistant schizophrenia: a cross-sectional study of a long-term follow-up cohort

BMC Psychiatry, 2018
Background Approximately one-third of schizophrenia patients eventually develop treatment-resistant schizophrenia (TRS). Although the time course of TRS development varies from patient to patient, the details of these variations have not been clarified ...
Nobuhisa Kanahara, Hiroshi Yamanaka, Tomotaka Suzuki, Masayuki Takase, Masaomi Iyo   +4 more
doaj   +1 more source