Results 61 to 70 of about 6,481,455 (307)
Negative Symptoms and Emotions in Schizophrenia [PDF]
Schizophrenia Bulletin, 1989 A 32-year-old man, who has suffered from schizophrenia for 12 years, has been rated by five professionals using the Scale for the Assessment of Negative Symptoms. These ratings are compared with samples of the patient's writing, which reflect his emotions.
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Physical appearance perfectionism explains variance in eating disorder symptoms above general perfectionism [PDF]
, 2015 Physical appearance perfectionism is a domain-specific form of perfectionism comprising two components: hope for perfection and worry about imperfection (Yang & Stoeber, 2012).
Stoeber, Joachim, Yang, Hongfei
core +1 more source
Pervalence of Negative Symptoms in Schizophrenia
Journal of Rehabilitation, 2002 Objective: Negative symptoms in schizophrenia are among the most important barriers against rehabilitation of such patients. Apply of appropriate drugs for reducing such symptoms and take help from psychosocial treatments, especially social skills ...
Saeed Shoja-Shefti, Maryam Bakhtiyari
doaj
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Dysfunctional Cognitions: Associations with Perfectionistic Thinking Utilizing the Positive and Negative Perfectionism Construct [PDF]
, 2004 Historically, perfectionism has been associated with symptomatologies such as depression, anxiety, and procrastination (Hewitt & Flett, 1991). However, a newer construct expands and includes both positive and negative aspects to perfectionism (Flett ...
Nyland, Jennifer E.
core
, 2021 To explore the relationship between negative affect, mind-wandering, rumination and obsessive-compulsive symptoms, 100 patients with obsessive-compulsive disorder and 100 healthy controls were assessed using the Obsessive-Compulsive Inventory, the Beck ...
Wang, Pengchong +8 more
core +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source