Results 61 to 70 of about 2,776,258 (309)

Does Combined Antipsychotic Treatment Provide Better Control on Symptoms in Patients with Schizophrenia than the Monotherapy?

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: Combined antipsychotic treatment is frequently used in clinical practice either to improve the symptom control or to reduce the severity of side effects.
Ersin Hatice Karslioglu   +8 more
doaj   +1 more source

Attitudes Toward Autism [PDF]

open access: yes, 2009
Many studies have been conducted to observe the effect of contact on attitudes toward people with mental illnesses, but few studies have observed the effect of contact on attitudes toward individuals on the autism spectrum specifically.
Edyvean, Carrie
core   +2 more sources

The Consequences of Perfectionism Scale: Factorial structure and relationships with perfectionism, performance perfectionism, affect, and depressive symptoms [PDF]

open access: yes, 2013
This study investigated the Consequences of Perfectionism Scale (COPS) and its relationships with perfectionism, performance perfectionism, affect, and depressive symptoms in 202 university students using confirmatory factor analysis, correlations, and ...
Hoyle, Alison J.   +2 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Сariprazine in the treatment of schizophrenia spectrum disorders in a hospital setting

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2023
The aim of the study was to evaluate the possibility of using cariprazine for the treatment of productive and negative symptoms in schizophrenic spectrum disorders in a hospital setting.Materials and methods: A group of 35 patients with leading ...
O. V. Limankin   +5 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Pervalence of Negative Symptoms in Schizophrenia

open access: yesJournal of Rehabilitation, 2002
Objective: Negative symptoms in schizophrenia are among the most important barriers against rehabilitation of such patients. Apply of appropriate drugs for reducing such symptoms and take help from psychosocial treatments, especially social skills ...
Saeed Shoja-Shefti, Maryam Bakhtiyari
doaj  

Let’s Talk: A Study of the Impact of Gendered Racial Socialization on African American Adolescent Girls’ Mental Health [PDF]

open access: yes, 2020
Internalized racial oppression in African American girls is understudied within research. As people of color are victimized by racism, they may internalize it, developing ideas, beliefs, actions and behaviors that support or collude with racism (Bivens ...
Allen, Keyona   +3 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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