Results 51 to 60 of about 6,481,455 (307)
Negative affect symptoms, anxiety sensitivity, and vasomotor symptoms during perimenopause
Objective: Vasomotor symptoms affect 60-80% of women during the menopausal transition. Anxiety, depression, and anxiety sensitivity can have an important role in the distressful experience of vasomotor symptoms. Our aim was to evaluate the prevalence and
Marianna de B. Jaeger +5 more
doaj +1 more source
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Insight in schizophrenia: Relationship to positive, negative and neurocognitive dimensions
Impairment of insight is considered as the hallmark of schizophrenia. Substantial proportion of patients with schizophrenia has either poor or absent insight.
Boban Joseph +2 more
doaj +1 more source
Introduction Social connectedness might positively influence the course of clinical symptoms in people with psychotic disorders. Objectives This study examines satisfaction with social connectedness (SSC) as predictor of positive and negative symptoms ...
J.S. Vogel +6 more
doaj +1 more source
Negative Symptoms: Are They Indigenous to Schizophrenia? [PDF]
The sudden popularity of positive and negative symptoms (PNS) has probably arisen as a result of the need for an instrument for clustering schizophrenic patients into subgroups that would respond similarly to the various treatments. The relation of PNS to the three major models for the etiology of schizophrenia (disease, socioenvironmental, and ...
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Objective: The safety and efficacy profile of risperidone and olanzapine were compared in a double-blind trial that used doses widely accepted in clinical practice.
P. N. Suresh Kumar +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Сariprazine in the treatment of schizophrenia spectrum disorders in a hospital setting
The aim of the study was to evaluate the possibility of using cariprazine for the treatment of productive and negative symptoms in schizophrenic spectrum disorders in a hospital setting.Materials and methods: A group of 35 patients with leading ...
O. V. Limankin +5 more
doaj +1 more source

