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Negative symptoms in schizophrenia—A review
Nordic Journal of Psychiatry, 2008Negative symptoms refer to the weakening or lack of normal thoughts, emotions or behaviour in schizophrenia patients. Their prevalence in first-episode psychosis is high, 50-90%, and 20-40% of schizophrenia patients have persisting negative symptoms. Severe negative symptoms during the early stages of treatment predict poor prognosis.
J, Mäkinen +3 more
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Novel antipsychotics and negative symptoms
International Clinical Psychopharmacology, 1998Negative symptoms are a key feature of schizophrenia. Novel (atypical) antipsychotic drugs, unlike conventional antipsychotics, cause substantial reductions in Positive and Negative Symptom Scale (PANSS) scores. Negative symptoms, however, can arise from both the pathology of the disease (primary negative symptoms) and as side effects of antipsychotic ...
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Negative Symptoms in Schizophrenia
Archives of General Psychiatry, 1982Recently, a renaissance of interest in "negative symptoms," eg, affective flattening or impoverishment of speech and language, has occurred. Although some investigators believe that these symptoms are important indicators of outcome, of response to treatment, and perhaps of a distinct, underlying pathologic process, research on the negative-symptom ...
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Rumination and Negative Symptoms in Schizophrenia
Journal of Nervous & Mental Disease, 2009Rumination is thought to be an important maintaining factor in depression. Depressive symptomatology is also a prominent feature in schizophrenia. However, little is known about the relationship between rumination and symptoms, such as depression and negative symptoms, in schizophrenia.
Halari, Rozmin +5 more
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Abstract Contemporary understandings typically view negative symptoms as fixed, individual “deficits” with biological underpinnings. These conceptualizations neglect the importance of social, political, and structural influences and determinants of experiences commonly called “negative symptoms.” This chapter explores alternative ...
Marie Brown, Shannon Pagdon, Nev Jones
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Marie Brown, Shannon Pagdon, Nev Jones
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Negative symptoms in Alzheimer's disease
American Journal of Psychiatry, 1996This study was undertaken to demonstrate that negative symptoms are prominent in patients with Alzheimer's disease and are distinct from depression.patients with Alzheimer's disease (N=24) and a group of cognitively intact older adults (N=26) were compared in terms of scores on the Scale for the Assessment of Negative Symptoms in Alzheimer's Disease ...
W E, Reichman +4 more
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Negative symptoms: another differential
Australasian Psychiatry, 2012Objective: The aim of this article is to describe a complex case of apparent flat affect in a particular workplace. Conclusion: Mafia operatives display apparent flat affect during working hours.
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Positive and negative symptoms in schizophrenia
Psychiatry Research, 1984Negative and positive symptoms were determined for 46 drug-free patients who met Research Diagnostic Criteria (RDC) and/or Feighner criteria for schizophrenia. A modified version of the Scale for the Assessment of Negative Symptoms (SANS) was completed for each patient based on items from the Schedule for Affective Disorders and Schizophrenia (SADS ...
W G, Rosen +6 more
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Neural Mechanisms of Negative Symptoms
British Journal of Psychiatry, 1989When Kraepelin originally defined and described dementia praecox, he assumed that it was due to some type of neural mechanism. He hypothesised that abnormalities could occur in a variety of brain regions, including the prefrontal, auditory, and language regions of the cortex.
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Evidence for the Validity of Negative Symptoms
2015Les symptomes negatifs de la schizophrenie: revue de la litterature sur l'interet et la validite scientifique de ce ...
T R, Barnes, P F, Liddle
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