A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Pimavanserin as an Adjunctive Treatment for the Negative Symptoms of Schizophrenia (ADVANCE-2) in Patients With Predominant Negative Symptoms. [PDF]
Bugarski-Kirola D +3 more
europepmc +1 more source
Interventions for negative symptoms in schizophrenia: efficacy and clinical interpretability in a meta-analysis of 451 randomized controlled trials. [PDF]
Damiani S +24 more
europepmc +1 more source
A proof-of-concept study: investigating the impact of COMT genotype and proline on negative symptoms in Alzheimer's disease. [PDF]
Clelland JD +10 more
europepmc +1 more source
Discrepancies between ideal and actual affect predict negative symptoms in schizophrenia in daily life: An ecological momentary assessment study. [PDF]
Luther L +7 more
europepmc +1 more source
Computational phenotypes underlying effort-based decision-making and negative symptoms in a transdiagnostic severe mental illness sample. [PDF]
Luther L +17 more
europepmc +1 more source
Neurobiological background of negative symptoms
Studies investigating neurobiological bases of negative symptoms of schizophrenia failed to provide consistent findings, possibly due to the heterogeneity of this psychopathological construct. We tried to review the findings published to date investigating neurobiological abnormalities after reducing the heterogeneity of the negative symptoms construct.
GALDERISI, Silvana +2 more
openaire +4 more sources

