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Efficacy and safety of rTMS for global symptom severity, negative symptoms, and auditory hallucinations in treatment-resistant schizophrenia: a systematic review and meta-analysis. [PDF]
Front PsychiatryAlhassan MA +5 more
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Secondary negative symptoms — A review of mechanisms, assessment and treatment [PDF]
Schizophrenia Research, 2017 Negative symptoms in schizophrenia may be classified as primary or secondary. Primary negative symptoms are thought to be intrinsic to schizophrenia, while secondary negative symptoms are caused by positive symptoms, depression, medication side-effects ...
André Aleman +2 more
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Antipsychotic drugs for patients with schizophrenia and predominant or prominent negative symptoms: a systematic review and meta-analysis [PDF]
European Archives of Psychiatry and Clinical Neuroscience, 2018 BACKGROUND Negative symptoms are the core of schizophrenia, but whether antipsychotics are efficacious for their treatment is unclear. Moreover, there is debate whether patients in relevant trials should have predominant negative symptoms or whether ...
Adriani Nikolakopoulou +2 more
exaly +4 more sources
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Cluster analysis of negative symptoms identifies distinct negative symptom subgroups
Schizophrenia Research, 2022The heterogeneity of schizophrenia has been acknowledged for decades because of the diverse presentation of symptoms, illness course, and treatment response noted between individuals diagnosed with the disorder. Cluster analysis has been used as a statistical method to determine whether schizophrenia subgroups might be identified based on symptom ...
Nina B, Paul +5 more
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The Concept of Negative Symptoms
British Journal of Psychiatry, 1989In a recent edition of the Schizophrenia Bulletin devoted to negative symptoms, the editor suggested at the beginning of his preface that what he called the “positive–negative symptom distinction” had been introduced into psychiatry only a decade previously (Levine, 1985).
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Transdiagnostic approach to negative symptoms
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2022The article provides a review of the literature on changes in views on negative symptoms, from historical aspects to modern research (clinical, neuroimaging), allowing them to be considered within the framework of a transdiagnostic approach.
K.V. Zakharova +3 more
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The Negative Symptom Challenge
Archives of General Psychiatry, 1992Fenton and McGlashan 1 note the relatively recent attention to the proposition that deficit or negative symptoms in schizophrenia have a distinct pathophysiologic process from that which underlies the production of positive psychotic symptoms. Although the attention is new, the proposition is not.
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Psychological Treatments for Negative Symptoms
British Journal of Psychiatry, 1989The subject matter of this paper is the psychological treatment of negative symptoms. However, before embarking on a review of the available literature, it is worthwhile considering some conceptual issues and distinctions which are relevant to research in this area.
P, Slade, R, Bentall
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