Results 181 to 190 of about 5,358,058 (362)

Can Democratic “We” Be Thought? The Politics of Negativity in Nihilistic Times

open access: yesPhilosophies
In this article I attempt to systematically reconstruct Theodor Adorno’s account of the relationship between the processes of authoritarian subject formation and the processes of political formation of the democratic common will.
Agustín Lucas Prestifilippo
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Wigner negativity and nonlocal correlations [PDF]

open access: yes
We investigate whether negative values of Wigner functions purely coming from correlations are sufficient for observing nonlocal correlations. We employ a simple model for superpositions of coherent states and examine how the corresponding Wigner ...
Michael E. N. Tschaffon   +1 more
core   +1 more source

Going Negative on Facebook: Negative User Expressions and Political Parties’ Reactions in the 2013 Austrian National Election Campaign

open access: yesInternational Journal of Communication, 2018
Social media platforms like Facebook are the new neighborhood pubs. Citizens often use these new public forums to talk about their anger and lack of faith in politics.
Uta Russmann
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Negativity and its capacity in JT gravity [PDF]

open access: yes
We study the refined Rényi negativity in the matrix model of Jackiw-Teitelboim (JT) gravity. We first consider the JT gravity with dynamical branes, which serves as a toy model of the evaporating black hole.
Takeshi Tachibana, Kazumi Okuyama
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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