Results 161 to 170 of about 5,358,058 (362)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reprezentări ale străinului în imaginarul colectiv românesc

open access: yesPhilologia
The article explores the complexity of the concept of the stranger, as analyzed through the lens of prominent philosophers of language, theorists, and literary critics such as Martin Buber, Franz Rosenzweig, Hans Gadamer, Karl Jaspers, Martin ...
Olesea GÎRLEA, Sergiu COGUT
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Unfavorable Prognostic Impact of HER2 2+/FISH-Negativity in Older Patients with HER2-Negative and High-Risk Breast Cancer [PDF]

open access: yes
Hao Wang,1 Miao Yu,1 Meihua Chen,2 Hui Li,1 Shiwei Liu1 1Department of Breast, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and ...
Li H, Yu M, Chen M, Wang H, Liu S
core   +1 more source

Divisive, Negative, and Populist?! An Empirical Analysis of European Populist and Mainstream Parties’ Use of Digital Political Advertisements

open access: yesInternational Journal of Communication
For digital political advertising (DPA) on Facebook, parties can complement their organic communication by targeting users with sponsored posts (Facebook-sponsored posts) and advertising campaigns (Facebook ads).
Simon Kruschinski   +9 more
doaj  

Dynamics of entanglement of qubits in the three-qubit Tavis — Cummings model with dipole-dipole interaction

open access: yesВестник Самарского университета: Естественнонаучная серия
The article studies the dynamics of pairwise entanglement of three qubits, two of which are trapped in a resonator and interact with a single-mode ideal resonator through single-photon transitions, and the third qubit is outside the resonator. This takes
Alexander R. Bagrov, Eugene K. Bashkirov
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Negative Theory

open access: yes, 2019
The work is solved in the context of the origin of the universe and matter. I build on a modified version of the vacuum energy that I use to formulate the whole theory. This work addresses the increasingly important matter of matter in space. The aim of this work is to modify the theory of the origin of the universe and to show how all matter in the ...
openaire   +1 more source

NEGATIVE THOUGHTS AND SELF-CONFIDENCE AMONG ATHLETES WITH DIFFERENT SPORTS EXPERIENCES: A META-ANALYSIS

open access: yesPsychTech & Health Journal
An athlete’s sporting experience is a factor associated with better-coping strategies and emotional regulation, especially concerning competitive anxiety and its symptoms.
José Vasconcelos-Raposo   +4 more
doaj   +1 more source

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