Results 131 to 140 of about 1,297,038 (311)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Awareness of child abuse and neglect among teachers of urban and rural schools – A comparative study

open access: yesJournal of Family Medicine and Primary Care
Context: Child abuse and neglect (CAN) remains a pressing issue worldwide, with teachers often being the first to notice signs of abuse in children. This study aims to compare the knowledge, attitudes, and practices (KAP) regarding CAN among primary ...
Zeba Kaunain   +5 more
doaj   +1 more source

Opinion: Too Many Veterans with Children are Still Homeless

open access: yes, 2014
Don’t ignore homeless veterans. As we pause this Veterans Day to reflect on those who have sacrificed in the service of our country, let us not neglect to address the plight of those who have returned to a civilian life with far less promise than they ...
Fee, Christopher R., Stewart, Joshua L.
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Types of Parental Attitude towards Children as a Way to Achieve Adaptive Family Relationships

open access: yesПроблеми сучасної психології
The purpose of this article is to study types of parental attitude towards children as a way to achieve adaptive family relationships. Methods of the research.
Nataliia Kharchenko
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

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