Results 131 to 140 of about 1,299,940 (312)
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Awareness of child abuse and neglect among teachers of urban and rural schools – A comparative study
Journal of Family Medicine and Primary CareContext: Child abuse and neglect (CAN) remains a pressing issue worldwide, with teachers often being the first to notice signs of abuse in children. This study aims to compare the knowledge, attitudes, and practices (KAP) regarding CAN among primary ...
Zeba Kaunain +5 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Types of Parental Attitude towards Children as a Way to Achieve Adaptive Family Relationships
Проблеми сучасної психологіїThe purpose of this article is to study types of parental attitude towards children as a way to achieve adaptive family relationships. Methods of the research.
Nataliia Kharchenko
doaj +1 more source
Neglected Populations, Neglected Diseases [PDF]
European Heart Journal, 2018 openaire +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source