Results 151 to 160 of about 864,462 (313)

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Youth in global environmental negotiations: The YouthEarth dataset. [PDF]

Data Brief
Vergonjeanne A, Orsini A.
europepmc   +1 more source

Synergistic Sunlight‐Activated Photodynamic and Near‐Infrared‐Induced Mild Photothermal Therapy for Infected Wound Healing Using Functionalized Nano‐Bi2WO6 Composites

Advanced Science, EarlyView.
This work proposes a multifunctional Bi2WO6:Yb,Er@CuS@CS nanocomposite that integrates photodynamic therapy (PDT), near‐infrared‐triggered photothermal therapy (PTT), and Cu2+ release for infected wound repair. The nanocomposite demonstrates enhanced antibacterial efficacy via combined PDT, PTT, and Cu2+ release, effective immunomodulatory by mild ...
Yihao Sun, Liangrui He, Zhijun Shen, Yuxin Zhang, Yizhang Tang, Xujiang Yu, Jisi Zheng, Moran Huang, Wanwan Li, Lei Wang   +9 more
wiley   +1 more source

Assessment of IPAY 2027 Medicare drug price negotiation maximum fair prices with prices in most-favored nation reference countries. [PDF]

J Manag Care Spec Pharm
Gabriel N, Martin K, Cousin EM, Li KH, Grueger J, Sullivan SD.   +5 more
europepmc   +1 more source

Strikes and Holdouts in Wage Bargaining: Theory and Data [PDF]

We develop a private-information model of union contract negotiations in which disputes signal a firm's willingness to pay. Previous models have assumed that all labor disputes take the form of a strike. Yet a prominent feature of U.S.
Joseph S. Tracy, Peter Cramton
core  

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Access in all areas? A round-up of developments in market access and health technology assessment: part 13. [PDF]

J Comp Eff Res
Ramagopalan SV, Pannelay AJ.
europepmc   +1 more source

SUMMARY OF THE 25TH SESSION OF THE OF THE INTERGOVERNMENTAL PANEL ON CLIMATE CHANGE: [PDF]

The twenty-fifth session of the Intergovernmental Panel on Climate Change (IPCC-25) took place in Port Louis, Mauritius, from 26-28 April 2006. The meeting was attended by approximately 270 participants representing governments, UN agencies and non ...
Development Negotiations, Service Environment   +1 more
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Facilitators and barriers to the formulation of public policies on food and nutrition: A scoping review. [PDF]

PLOS Glob Public Health
Feldenheimer da Silva AC, Fagundes AA, Curioni CC, Ribeiro de Sá CC, Buccini G, Pereira-Castro MR, Lopes MS, Rocha LL, Pereira FMN, Recine E.   +9 more
europepmc   +1 more source