Detailed evaluation of data analysis tools for subtyping of bacterial isolates based on whole genome sequencing : Neisseria meningitidis as a proof of concept [PDF]
Whole genome sequencing is increasingly recognized as the most informative approach for characterization of bacterial isolates. Success of the routine use of this technology in public health laboratories depends on the availability of well-characterized ...
Bertrand, Sophie+5 more
core +3 more sources
Genetic Studies of Sulfadiazine-resistant and Methionine-requiring \u3cem\u3eNeisseria\u3c/em\u3e Isolated From Clinical Material [PDF]
Deoxyribonucleate (DNA) preparations were extracted from Neisseria meningitidis (four isolates from spinal fluid and blood) and N. gonorrhoeae strains, all of which were resistant to sulfadiazine upon primary isolation.
BROWN G. M.+35 more
core +4 more sources
Oropharyngeal carriage of potential meningitis-causing bacteria in a Ghanaian prison [PDF]
Background: Bacterial meningitis continues to be a global health problem even after introducing of meningococcal and pneumococcal vaccines. Surveillance of high-risk populations such as prisoners is necessary for timely identification of outbreaks and ...
Emmanuel Amewu+5 more
doaj +1 more source
Evaluation of procedures for typing of group B Streptococcus: a retrospective study [PDF]
Background This study evaluates two procedures for typing of Streptococcus agalactiae (group B streptococci; GBS) isolates, using retrospective typing data from the period 2010 to 2014 with a commercial latex agglutination test (latex test) and the ...
Hans-Christian Slotved, Steen Hoffmann
doaj +2 more sources
Vertebrate and Invertebrate Animal and New In Vitro Models for Studying Neisseria Biology
The history of Neisseria research has involved the use of a wide variety of vertebrate and invertebrate animal models, from insects to humans. In this review, we itemise these models and describe how they have made significant contributions to ...
Michael M. Girgis, Myron Christodoulides
doaj +1 more source
Vaccines are arguably one of the greatest advancements in modern medicine. Subunit vaccines comprise the majority of current preparations and consist of two main components—antigen and adjuvant.
Christina Lisk+6 more
doaj +1 more source
Antimicrobial resistance (AMR) is widespread within Neisseria gonorrhoeae populations. Recent work has highlighted the importance of commensal Neisseria (cN) as a source of AMR for their pathogenic relatives through horizontal gene transfer (HGT) of AMR ...
Maira Goytia, Crista B. Wadsworth
doaj +1 more source
Prediction of Prophages and Their Host Ranges in Pathogenic and Commensal Neisseria Species
The genus Neisseria includes two pathogenic species, N. gonorrhoeae and N. meningitidis, and numerous commensal species. Neisseria species frequently exchange DNA with one another, primarily via transformation and homologous recombination and via ...
Giulia Orazi+2 more
doaj +1 more source
MafB proteins are toxins secreted by Neisseria spp. which are involved in interbacterial competition. Their secretion mechanism has so far not been elucidated. Each strain can produce several MafB variants. On the chromosome, the mafB genes are localized
Jesús Arenas+5 more
doaj +1 more source
Structural and Immunological Characterization of Novel Recombinant MOMP-Based Chlamydial Antigens
Chlamydia is the most common cause of bacterial sexually transmitted infections worldwide. While infections resolve with antibiotic treatment, this is often neglected in women due to frequent asymptomatic infections, leading to disease progression and ...
Guillermo Madico+3 more
doaj +1 more source