Results 21 to 30 of about 101,309 (212)

Update on the Neisseria Macrophage Infectivity Potentiator-Like PPIase Protein

Frontiers in Cellular and Infection Microbiology, 2022
Neisseria pathogens express a Macrophage Infectivity Potentiator Protein (MIP), which belongs to the FK506 binding protein (FKBP) family of proteins that exhibit peptidyl-prolyl cis/trans isomerase (PPIase) activity.
Myron Christodoulides
doaj   +1 more source

The Adhesin Complex Protein (ACP) of Neisseria meningitidis Is a New Adhesin with Vaccine Potential

mBio, 2013
The acp gene encoding the 13-kDa adhesin complex protein (ACP) from Neisseria meningitidis serogroup B strain MC58 was cloned and expressed in Escherichia coli, and the purified recombinant ACP (rACP) was used for immunization studies.
Miao-Chiu Hung, John E. Heckels, Myron Christodoulides   +2 more
doaj   +1 more source

A Novel Method to Assess Antimicrobial Susceptibility in Commensal Oropharyngeal Neisseria—A Pilot Study

Antibiotics, 2022
Commensal Neisseria provide a reservoir of resistance genes that can be transferred to the pathogens Neisseria gonorrhoeae and N. meningitidis in the human oropharynx. Surveillance programs are thus needed to monitor resistance in oropharyngeal commensal
Jolein Gyonne Elise Laumen, Saïd Abdellati, Christophe Van Dijck, Delphine Martiny, Irith De Baetselier, Sheeba Santhini Manoharan-Basil, Dorien Van den Bossche, Chris Kenyon   +7 more
doaj   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Structure of the Recombinant Neisseria gonorrhoeae Adhesin Complex Protein (rNg-ACP) and Generation of Murine Antibodies with Bactericidal Activity against Gonococci

mSphere, 2018
Neisseria gonorrhoeae (gonococcus [Ng]) is the causative organism of the sexually transmitted disease gonorrhoea, and no effective vaccine exists currently.
Hannia Liliana Almonacid-Mendoza, María Victoria Humbert, Aiste Dijokaite, David W. Cleary, Yiwen Soo, Miao-Chiu Hung, Christian M. Orr, Moritz M. Machelett, Ivo Tews, Myron Christodoulides   +9 more
doaj   +1 more source

Et tu, Neisseria? Conflicts of Interest Between Neisseria Species

Frontiers in Cellular and Infection Microbiology, 2022
Neisseria meningitidis and Neisseria gonorrhoeae are two obligate human pathogens that have evolved to be uniquely adapted to their host. The meningococcus is frequently carried asymptomatically in the nasopharynx, while gonococcal infection of the ...
Rene Baerentsen, Christoph M. Tang, Rachel M. Exley   +2 more
doaj   +1 more source

Successful Intra- but Not Inter-species Recombination of msr(D) in Neisseria subflava

Frontiers in Microbiology, 2022
Resistance acquisition via natural transformation is a common process in the Neisseria genus. Transformation has played an important role in the emergence of resistance to many antimicrobials in Neisseria gonorrhoeae and Neisseria meningitidis.
Tessa de Block, Natalia González, Saïd Abdellati, Jolein Gyonne Elise Laumen, Jolein Gyonne Elise Laumen, Christophe Van Dijck, Christophe Van Dijck, Irith De Baetselier, Dorien Van den Bossche, Sheeba S. Manoharan-Basil, Chris Kenyon, Chris Kenyon   +11 more
doaj   +1 more source

First antimicrobial resistance data and genetic characteristics of Neisseria gonorrhoeae isolates from Estonia, 2009–2013

New Microbes and New Infections, 2014
Gonorrhoea is a sexually transmitted infection with major public health implications and Neisseria gonorrhoeae has developed resistance to all antimicrobials introduced for treatment. Enhanced surveillance of antimicrobial resistance in N. gonorrhoeae is
D. Golparian, T. Brilene, Y. Laaring, E. Viktorova, E. Johansson, M. Domeika, M. Unemo   +6 more
doaj   +1 more source

Detailed Evaluation of Data Analysis Tools for Subtyping of Bacterial Isolates Based on Whole Genome Sequencing: Neisseria meningitidis as a Proof of Concept

Frontiers in Microbiology, 2019
Whole genome sequencing is increasingly recognized as the most informative approach for characterization of bacterial isolates. Success of the routine use of this technology in public health laboratories depends on the availability of well-characterized ...
Assia Saltykova, Assia Saltykova, Wesley Mattheus, Sophie Bertrand, Nancy H. C. Roosens, Kathleen Marchal, Kathleen Marchal, Sigrid C. J. De Keersmaecker   +7 more
doaj   +1 more source

Antigenicity in mice of a recombinant Neisseria gonorrhoeae MafA 2/3 protein

Virulence
There are no prophylactic vaccines for preventing the disease gonorrhea, caused by sexually transmitted infection with the Gram-negative pathogen Neisseria gonorrhoeae.
Michael M Girgis, Maria Victoria Humbert, Christopher J McCormick, Myron Christodoulides   +3 more
doaj   +1 more source