Results 61 to 70 of about 114,622 (193)

Genomic characterization of novel Neisseria species

Scientific Reports, 2019
Of the ten human-restricted Neisseria species two, Neisseria meningitidis, and Neisseria gonorrhoeae, cause invasive disease: the other eight are carried asymptomatically in the pharynx, possibly modulating meningococcal and gonococcal infections ...
Kanny Diallo, J. Maclennan, O. Harrison, C. Msefula, S. Sow, D. Daugla, Errin Johnson, C. Trotter, C. MacLennan, J. Parkhill, R. Borrow, B. Greenwood, M. Maiden   +12 more
semanticscholar   +1 more source

Immunoglobulin A nephropathy is characterized by anticommensal humoral immune responses

JCI Insight, 2022
IgA nephropathy (IgAN) is a leading cause of kidney failure, yet little is known about the immunopathogenesis of this disease. IgAN is characterized by deposition of IgA in the kidney glomeruli, but the source and stimulus for IgA production are not ...
Elissa G. Currie, Bryan Coburn, Elisa A. Porfilio, Ping Lam, Olga L. Rojas, Jan Novak, Stuart Yang, Raad B. Chowdhury, Lesley A. Ward, Pauline W. Wang, Khashayar Khaleghi, James An, Sarah Q. Crome, Michelle A. Hladunewich, Sean J. Barbour, Daniel C. Cattran, Rulan S. Parekh, Christoph Licht, Rohan John, Rupert Kaul, Kenneth Croitoru, Scott D. Gray-Owen, David S. Guttman, Jennifer L. Gommerman, Heather N. Reich   +24 more
doaj   +1 more source

Commensal Neisseria Are Shared between Sexual Partners: Implications for Gonococcal and Meningococcal Antimicrobial Resistance

Pathogens, 2020
Antimicrobial resistance in pathogenic Neisseria parallels reduced antimicrobial susceptibility in commensal Neisseria in certain populations, like men who have sex with men (MSM).
Christophe Van Dijck, Jolein G. E. Laumen, Sheeba S. Manoharan-Basil, Chris Kenyon   +3 more
doaj   +1 more source

Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of Neisseria gonorrhoeae Possessing a Mosaic-Like mtr Efflux Pump Locus

mBio, 2018
Historically, after introduction of an antibiotic for treatment of gonorrhea, strains of N. gonorrhoeae emerge that display clinical resistance due to spontaneous mutation or acquisition of resistance genes.
Corinne E. Rouquette-Loughlin, Jennifer L. Reimche, J. T. Balthazar, Vijaya L Dhulipala, K. Gernert, E. Kersh, C. Pham, Kevin Pettus, A. J. Abrams, D. Trees, S. S. St. Cyr, W. Shafer   +11 more
semanticscholar   +1 more source

Sweet complexity: O-linked protein glycosylation in pathogenic Neisseria

Frontiers in Cellular and Infection Microbiology
The genus Neisseria, which colonizes mucosal surfaces, includes both commensal and pathogenic species that are exclusive to humans. The two pathogenic Neisseria species are closely related but cause quite different diseases, meningococcal sepsis and ...
Bente Børud, Michael Koomey
doaj   +1 more source

Structure of the Neisseria meningitidis Type IV pilus

Nature Communications, 2016
Neisseria meningitidis use Type IV pili (T4P) to adhere to endothelial cells and breach the blood brain barrier, causing cause fatal meningitis. T4P are multifunctional polymers of the major pilin protein, which share a conserved hydrophobic N terminus ...
S. Kolappan, Mathieu Coureuil, Xiong Yu, X. Nassif, E. Egelman, L. Craig   +5 more
semanticscholar   +1 more source

Sulphonamide resistant commensal Neisseria with alterations in the dihydropteroate synthase can be isolated from carriers not exposed to sulphonamides

BMC Microbiology, 2002
Background Development of sulphonamide resistance in Neisseria meningitidis has been suggested to involve horizontal DNA-transfer from a commensal Neisseria species.
Swedberg Göte, Qvarnström Yvonne
doaj   +1 more source

Neisseria species as pathobionts in bronchiectasis.

Cell Host and Microbe, 2022
Liang Li, M. Mac Aogáin, T. Xu, T. Jaggi, Louisa L Y Chan, Jing Qu, Lan Wei, Shumin Liao, H. Cheng, Holly R. Keir, A. Dicker, Kai Sen Tan, Wang De Yun, M. Koh, T. Ong, A. Lim, J. Abisheganaden, T. B. Low, T. Hassan, Xiang Long, P. Wark, B. Oliver, Daniela I. Drautz-Moses, S. Schuster, N. Tan, M. Fang, J. Chalmers, S. H. Chotirmall   +27 more
semanticscholar   +1 more source

The nonpathogenic commensal Neisseria: friends and foes in infectious disease.

Current Opinion in Infectious Diseases, 2019
PURPOSE OF REVIEW Nonpathogenic commensal Neisseria are rarely considered in the clinical setting despite evidence that they can cause invasive opportunistic infections.
R. Dorey, A. Theodosiou, R. Read, C. Jones   +3 more
semanticscholar   +1 more source

Oropharyngeal microbiome evaluation highlights Neisseria abundance in active celiac patients

Scientific Reports, 2018
We previously profiled duodenal microbiome in active (a-), gluten-free diet (GFD) celiac disease (CD) patients and controls finding higher levels of the Proteobacterium Neisseria flavescens in a-CD patients than in the other two groups.
Laura Iaffaldano, Ilaria Granata, C. Pagliuca, M. V. Esposito, G. Casaburi, G. Salerno, R. Colicchio, Marina Piccirillo, C. Ciacci, G. Del Vecchio Blanco, M. Guarracino, P. Salvatore, F. Salvatore, V. D’Argenio, L. Sacchetti   +14 more
semanticscholar   +1 more source