Background Antimicrobial resistance in gonorrhea has become a growing global public health burden. Neisseria gonorrhoeae isolates with resistance to ceftriaxone, the last remaining first-line option, represent an emerging threat of untreatable gonorrhea.
Di Wang +7 more
doaj +1 more source
Phenotypic and genotypic characterisation of Neisseria gohorrhoeae isolates from New Zealand with reduced susceptibility to ceftriaxone : a thesis submitted to the College of Health in partial fulfilment of the requirements for the Master of Science in Microbiology at Massey University, New Zealand [PDF]
Objectives Currently, ceftriaxone is the last remaining drug recommended for empirical treatment of gonorrhoea. Neisseria gonorrhoeae with reduced susceptibility to ceftriaxone have been isolated worldwide in countries such as Japan, France, Spain ...
Mohd Jamaludin, Norshuhaidah bt
core
ABSTRACT Background Sexually transmitted infections (STIs), caused by Neisseria gonorrhoeae, Treponema pallidum and Chlamydia trachomatis, are increasing across Europe, which prompts dermatologists to be more involved in their detection and management.
Andrei Tanasov +6 more
wiley +1 more source
Opportunity and Means: Horizontal Gene Transfer from the Human Host to a Bacterial Pathogen
The acquisition and incorporation of genetic material between nonmating species, or horizontal gene transfer (HGT), has been frequently described for phylogenetically related organisms, but far less evidence exists for HGT between highly divergent ...
Mark T. Anderson, H. Steven Seifert
doaj +1 more source
The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria [PDF]
Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm.
A Baslé +95 more
core +1 more source
Conjugative Plasmids of Neisseria gonorrhoeae
Many clinical isolates of the human pathogen Neisseria gonorrhoeae contain conjugative plasmids. The host range of these plasmids is limited to Neisseria species, but presence of a tetracycline (tetM) determinant inserted in several of these plasmids is an important cause of the rapid spread of tetracycline resistance.
Chris van der Does, Emilia Pachulec
openaire +6 more sources
Composition of the lipopolysaccharide of Neisseria gonorrhoeae [PDF]
Analysis of glycose and fatty acid content of lipopolysaccharide extracted from 38 strains of Neisseria gonorrhoeae indicated that glycoses common to colonial types 1 to 5 were glucose, mannose, and galactose, N-acetylneuraminic acid, 2-keto-3-deoxyoctulosonic acid (KDO), glucosamine, and galactosamine were also invariably present.
G. M. Wiseman, J D Caird
openaire +3 more sources
Glycoproteomics and Its Role in Understanding Bacterial O‐Linked Glycosylation
ABSTRACT Protein glycosylation is now recognized as a ubiquitous process observed in all domains of life. Within bacterial species, carbohydrates can be attached to multiple residues with glycosylation of serine, threonine, or tyrosine residues via their hydroxyl side chains referred to as O‐linked glycosylation.
Kristian I. Karlic +2 more
wiley +1 more source
The use of current genotyping assay methods for Neisseria gonorrhoeae
The review deals with up-to-date genotyping assay methods of Neisseria gonorrhoeae. The review covers the characteristics and features of each method, application areas of genotyping assay of Neisseria gonorrhoeae. The methods described enable to upgrade
M. V. Shpilevaya +2 more
doaj +1 more source
Horizontal gene transfer (HGT) in the penA and multidrug efflux pump genes has been shown to play a key role in the genesis of antimicrobial resistance in Neisseria gonorrhoeae. In this study, we evaluated if there was evidence of HGT in the genes coding
Sheeba Santhini Manoharan-Basil +8 more
doaj +1 more source

