Molecular Pathogenesis of Neisseria Gonorrhoeae [PDF]
This Research Topic is focused on the molecular mechanisms of pathogenesis employed by the obligate human pathogen, Neisseria gonorrhoeae. The 10 articles cover a range of topics, including updates on important virulence factors, vaccine development efforts, immune evasion by the gonococcus, and current models for assessing virulence, treatments, and ...
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Neopterin is a sensitive and specific biomarker of intracellular pathogen infection and chronic inflammation, and affected by environmental, life‐history, and sex‐contextual factors. This review offers best‐practice guidelines and practical advice on sample collection, storage, and analysis in primates when used for ecoimmunological conservation and ...
Verena Behringer, Caroline Deimel
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Update on Laboratory Diagnosis and Epidemiology of \u3cem\u3eTrichomonas vaginalis\u3c/em\u3e: You Can Teach an “Old” Dog “New” Trichs [PDF]
Past viewpoints on Trichomonas vaginalis infection have characterized the associated clinical disease as a “nuisance” condition, with affected demographics largely being older African American females residing in urban centers.
Munson, Erik +2 more
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Pregnancy and contraceptive use among women participating in an HIV prevention trial in Tanzania. [PDF]
OBJECTIVES: Information on pregnancy rates and factors associated with pregnancy and contraceptive use is important for clinical trials in women in sub-Saharan Africa where withdrawal of investigational products may be required in the event of pregnancy ...
Baisley, Kathy +8 more
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Obtaining self-samples to diagnose curable sexually transmitted infections: a systematic review of patients' experiences [PDF]
BACKGROUND: Routine screening is key to sexually transmitted infection (STI) prevention and control. Previous studies suggest that clinic-based screening programmes capture only a small proportion of people with STIs.
Lau, Jason +4 more
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ABSTRACT Actinobacillus succinogenes is a ruminal microorganism of biotechnological importance due to its capacity to produce succinic acid at high yields. Despite the scientific interest in this organism, molecular vehicles for the transfer and expression of genetic material are limited compared to the existing demand.
Angélica Vallejo‐Giraldo +7 more
wiley +1 more source
Antimicrobial susceptibility of Neisseria gonorrheae strains in three regions of Armenia [PDF]
OBJECTIVE: There are no data available on gonococcal susceptibility in the Caucasus region. We aimed to determine in vitro antimicrobial susceptibility of Neisseria gonorrheae in Armenia in order to update the national treatment protocol.
Borisenko +6 more
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Production of a capsule of Neisseria gonorrhoeae [PDF]
Neisseria gonorrhoeae can be induced to form a large capsule that can be visualized with India ink. Encapsulated gonococci appeared to be resistant to non-antibody-mediated phagocytosis compared with unencapsulated gonococci of the same strain and colony type.
W P Richardson, J C Sadoff
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CRISPR‐driven diagnostics: Molecular mechanisms, clinical efficacy and translational challenges
The CRISPR/Cas system has emerged as a transformative tool in the field of molecular diagnosis, offering unprecedented sensitivity, specificity and rapid detection capabilities. This review further examines the molecular mechanisms of CRISPR tools, compares their clinical efficacy with traditional methods and highlights cutting‐edge innovations such as
Zilong Wang +7 more
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Genetic Studies of Sulfadiazine-resistant and Methionine-requiring \u3cem\u3eNeisseria\u3c/em\u3e Isolated From Clinical Material [PDF]
Deoxyribonucleate (DNA) preparations were extracted from Neisseria meningitidis (four isolates from spinal fluid and blood) and N. gonorrhoeae strains, all of which were resistant to sulfadiazine upon primary isolation.
BROWN G. M. +35 more
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