BACTERIAL OUTER MEMBRANE VESICLES AND VACCINE APPLICATIONS [PDF]
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of self ...
Reinaldo eAcevedo +10 more
doaj +5 more sources
Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18. [PDF]
The bacterium Neisseria meningitidis is commonly found harmlessly colonising the mucosal surfaces of the human nasopharynx. Occasionally strains can invade host tissues causing septicaemia and meningitis, making the bacterium a major cause of morbidity ...
Stephen D Bentley +20 more
doaj +3 more sources
The glycointeractome of serogroup B Neisseria meningitidis strain MC58
Neisseria meningitidis express numerous virulence factors that enable it to interact with diverse microenvironments within the host, during both asymptomatic nasopharyngeal colonization and invasive disease.
Tsitsi D. Mubaiwa +7 more
doaj +4 more sources
Complete Genome Sequence of Serogroup B Neisseria meningitidis Strain C311
Neisseria meningitidis strain C311 has been widely used to study meningococcal pathogenesis in the past 30 years, but its genome is not available. Here, we report that the complete C311 genome is 2,311,508 bp in length, contains a total of 2,274 genes, and has a GC content of 51.25%.
Freda E.-C. Jen +4 more
openaire +4 more sources
The electron transport chains of Neisseria meningitidis [PDF]
Neisseria meningitidis contains c-type and b-type cytochromes. Oxidation of c-type and b-type cytochromes by oxygen was observed in both cells grown under aerobic and denitrifying conditions, whereas oxidation of cytochromes by nitrite was only seen in ...
Deeudom, Manu
core +6 more sources
Adjuvants : an essential component of neisseria vaccines [PDF]
Adjuvants may be classified into delivery systems and immune potentiator or modulator molecules based on their mechanism of action. Neisseria vaccines containing traditional adjuvants such as aluminium salts have existed for long time, but meningitis ...
Acevedo, R. +8 more
core +4 more sources
The genetic characteristics of Neisseria meningitidis causing invasive meningococcal infections in Smolensk region [PDF]
Objective. To determine antigenic and genetic characteristics of Neisseria meningitidis isolated from the patients with invasive meningococcal infections in Smolensk region in comparison with those circulating in other regions. Materials and Methods.
Mironov K.O. +3 more
doaj +1 more source
Outer membrane vesicle of Neisseria meningitidis serogroup B as an adjuvant in immunization of rabbit against Neisseria meningitidis serogroup A [PDF]
Neisseria meningitidis serogroup B outer membrane vesicle (OMV) was revealed to be an efficient carrier for polysaccharide antigens such as capsular antigens. Also, OMV of N. meningitidis was shown to be able to induce high levels of antibodies when applied as an adjuvant for T-independent antigens.
Davar Siadat Seyed +8 more
openaire +1 more source
Production and Degradation of Serogroup B Neisseria meningitidis Polysaccharide [PDF]
Polysaccharide produced from cultures of serogroups A, B, and C Neisseria meningitidis was assayed by the serogroup-specific hemagglutination inhibition (HAI) test. The polysaccharide produced by all serogroups was found to increase during the exponential phase of growth. For serogroups A and C, the HAI activity was
P C, Maloney, H, Schneider, B L, Brandt
openaire +2 more sources
Genetic and Antigenic Diversity of <i>Neisseria meningitidis</i> Serogroup B Strains in Vietnam. [PDF]
Background: Neisseria meningitidis (N. meningitidis) is a leading cause of acute meningitis and is classified into 13 serogroups, six of which are predominantly associated with invasive meningococcal disease. This study aimed to investigate the genotype, subgenotype, and antigenic profiles of N.
Long TP +10 more
europepmc +4 more sources

