Results 61 to 70 of about 12,304,496 (201)

Microbiological epidemiological history of meningococcal disease in Rio de Janeiro, Brazil

Brazilian Journal of Infectious Diseases, 2010
The main objectives of the present study were to investigate the clinical and laboratory features of meningococcal disease in the city of Rio de Janeiro, Brazil, during the overlap of 2 epidemics in the 1990s. We conducted a study of a series of cases of
David Eduardo Barroso, MD PhD, D.M. Carvalho, S.T. Casagrande, M.C. Rebelo, V. Soares, V. Zahner, C.A. Solari, S.A. Nogueira   +7 more
doaj   +1 more source

Complement Inhibition in the Clinic: Are We Doing Enough to Protect Patients From Infection?

European Journal of Immunology, Volume 56, Issue 7, July 2026.
Excessive complement activation is implicated in a broad range of diseases. Therapeutic approaches targeting the complement cascade, from pathway‐selective inhibition to terminal blockade, can effectively control disease activity. However, increasing degrees of complement inhibition are associated with a heightened susceptibility to bacterial, viral ...
Serena Bettoni, Ebba Qviberg, Edward Chaloner, Hayley Lavender, Maisem Laabei   +4 more
wiley   +1 more source

Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp

Nature Communications, 2018
Factor H binding protein (fHbp) is a meningococcal virulence factor and a component of vaccines against serogroup B Neisseria meningitidis. Here, the authors characterize the vaccine-elicited human antibody Fab 1A12 and present both the free and the fHbp-
Jacinto López-Sagaseta, Peter T. Beernink, Federica Bianchi, Laura Santini, Elisabetta Frigimelica, Alexander H. Lucas, Mariagrazia Pizza, Matthew J. Bottomley   +7 more
doaj   +1 more source

Diversity in coding tandem repeats in related Neisseria spp. [PDF]

, 2003
This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL - © 2003 Jordan et al; licensee BioMed Central Ltd ...
Jordan, P, Snyder, Lori A S, Snyder, Lori, Snyder, LAS, Saunders, Nigel, Lori AS Snyder, Saunders, NJ, Jordan Philip, Snyder, LA, Jordan, Philip, Philip Jordan, Saunders Nigel J, Nigel J Saunders, Saunders, Nigel J, Snyder Lori AS   +14 more
core   +1 more source

Social Behavior and Meningococcal Carriage in British Teenagers

, 2006
Understanding predisposing factors for meningococcal carriage may identify targets for public health interventions. Before mass vaccination with meningococcal group C conjugate vaccine began in autumn 1999, we took pharyngeal swabs from ?14,000 UK ...
MacLennan, J., MacLennan, Jenny, Neal, K., Andrews, Nick, Kafatos, G, Cameron, J. Claire, J. Claire Cameron, Maiden, Martin C J, Kafatos, George, Keith Neal, Cann, Kathy, Evans, M.R., MacLennan, J, Cann, K, Kafatos, G., Cameron, JC, Roberts, Richard, Richard Roberts, Evans, MR, Nick Andrews, Martin C.J. Maiden, James M. Stuart, Evans, Meirion R., Neal, K, David N. Baxter, Maiden, MCJ, Stuart, J.M., Baxter, David N., Roberts, R., Cameron, J.C., Andrews, N., Maiden, M.C.J., Jenny MacLennan, Meirion R. Evans, George Kafatos, Kathy Cann, Andrews, N, Stuart, JM, Cann, K., Roberts, R, Baxter, DN, Stuart, James M., Baxter, D.N., Neal, Keith   +43 more
core   +2 more sources

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, Volume 13, Issue 29, 22 May 2026.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Host iron binding proteins acting as niche indicators for Neisseria meningitidis [PDF]

, 2009
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited - Copyright ...
Philip W Jordan, Jordan, Philip W., Philip W. Jordan, Jordan Philip W., Saunders Nigel J., Jordan, PW, Saunders, Nigel, Saunders, NJ, Nigel J Saunders, Saunders, Nigel J., Nigel J. Saunders   +10 more
core   +2 more sources

Monoclonal antibody to serotype 17 of Neisseria meningitidis and their prevalence in Brazilian States Anticorpo monoclonal contra o sorotipo 17 de Neisseria meningitidis e sua prevalência em estados brasileiros

Revista do Instituto de Medicina Tropical de São Paulo, 1995
Neisseria meningitidis are gram-negative diplococci responsible for cases of meningococcal disease all over the world. The epidemic potential of N.
Claudio Tavares Sacchi, Ana Paula Silva de Lemos, Maria Cecília Outeiro Gorla, Carl E. Frasch   +3 more
doaj   +1 more source

Product review on the IMD serogroup B vaccine Bexsero®

Human Vaccines & Immunotherapeutics, 2022
Bexsero® is a multicomponent vaccine composed of four major proteins of Neisseria meningitidis: the fHbp, NHBA, NadA and PorA. This vaccine was licensed against invasive meningococcal disease (IMD) due to serogroup B isolates.
Ala-Eddine Deghmane, Muhamed-Kheir Taha
doaj   +1 more source

Trends in Meningitis Burden and Projections to 2040: A Secondary Analysis of the Global Burden of Disease Study 2023

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Meningitis remains a global health challenge, characterized by substantial regional and etiologic disparities. This study aimed to analyze recent trends, forecast future burden, and examine the influence of development status on meningitis outcomes.
Mehdi Azizmohammad Looha, Ali Saberi Shahrbabaki, Fatemeh Masaebi, Mahmoud Zamani, Farid Zayeri   +4 more
wiley   +1 more source