Results 31 to 40 of about 53,214 (202)

Neisseria meningitidis and cytomegalovirus simultaneous detection in the filmarray meningitis/encephalitis panel and its clinical relevance

IDCases, 2019
A BioFire FilmArray Meningitis/Encephalitis test was performed on a 7-month old child suspected for bacterial meningitis. Two pathogens were detected, Neisseria meningitidis and cytomegalovirus (CMV).
Nadav Sorek, Shai Ashkenazi, Gilat Livni, Haim Ben-Zvi   +3 more
doaj   +1 more source

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

Angewandte Chemie, EarlyView.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster, Òscar Vidal‐Gironès, Rowan de Graaf, Ken Kok, Lindsey T. Lelieveld, Jackelien Hoogervorst, Maria J. Ferraz, José Pablo Rivas‐Fernández, Rob F. Lammers, Herman S. Overkleeft, Johannes M. F. G. Aerts, Rolf G. Boot, Carme Rovira, Marta Artola   +13 more
wiley   +2 more sources

Neisseria meningitidis Infecting a Prosthetic Knee Joint: A New Case of an Unusual Disease

Case Reports in Infectious Diseases, 2017
Primary meningococcal meningitis is an infrequent but known disease. However, the infection of a prosthetic joint with Neisseria meningitidis is rare.
Berta Becerril Carral, Elvira Alarcón Manoja, Salvador López Cárdenas, Jesús Canueto Quintero   +3 more
doaj   +1 more source

Host iron binding proteins acting as niche indicators for Neisseria meningitidis [PDF]

, 2009
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited - Copyright ...
Philip W Jordan, Jordan, Philip W., Philip W. Jordan, Jordan Philip W., Saunders Nigel J., Jordan, PW, Saunders, Nigel, Saunders, NJ, Nigel J Saunders, Saunders, Nigel J., Nigel J. Saunders   +10 more
core   +2 more sources

Nitro Reduction‐Based RNA Control and Ultrafast Release

Angewandte Chemie, EarlyView.
A chemical RNA caging–uncaging strategy based on nitro reduction is described. Nitroaryl groups introduced via acylation temporarily block the functions of diverse RNAs in vitro and in living cells. Treatment with a diboronic acid–bipyridine mixture rapidly reduces the nitro groups, releasing RNAs and restoring their activity.
Yiran Zhao, Senfeng Zhang, Junsong Guo, Tuan‐Khoa Kha, Song Chen, Chunyi Hu, Ru‐Yi Zhu   +6 more
wiley   +2 more sources

Identification of the nasopharyngeal carriage of Neisseria meningitidis by 16S rRNA Gene sequencing in asymptomatic adolescents and young adults in Cartagena, Colombia (2019–2020).

Brazilian Journal of Infectious Diseases, 2022
The bacterium Neisseria meningitidis, a strictly human pathogen, can cause meningitis, meningococcemia, sepsis, and death; repeatedly it scause outbreaks around the world.
Marlon Macias-Mendoza, Biol. MSc, Alfredo Montes-Robledo, Biol. MSc, Cindy Arteta-Acosta, MD, MPH, PhD (C), Rosa Baldiris-Avila, QF, PhD, Wilfrido Coronell-Rodríguez, MD, pediatric infectious disease, PhD.   +4 more
doaj   +1 more source

DNA methylation assessed by SMRT sequencing is linked to mutations in Neisseria meningitidis isolates [PDF]

, 2015
The Gram-negative bacterium Neisseria meningitidis features extensive genetic variability. To present, proposed virulence genotypes are also detected in isolates from asymptomatic carriers, indicating more complex mechanisms underlying variable ...
Gerd Pluschke, Christoph D. Schmid (72046), Schmid, Christoph D., Mane, Shrikant, Korlach, Jonas, Tyson A. Clark (105783), Katharina Röltgen, Wang, Guilin, Araceli Lamelas, Jonas Korlach (105788), Shrikant Mane, Araceli Lamelas (128475), Christoph D Schmid, Mohamad R Abdul Sater, Clark, Tyson A., Röltgen, Katharina, Gerd Pluschke (7855), Katharina Röltgen (120045), Guilin Wang, Sater, Mohamad R. Abdul, Tyson A Clark, Mohamad R. Abdul Sater (836669), Jonas Korlach, Guilin Wang (37620), Shrikant Mane (106631), Lamelas, Araceli, Pluschke, Gerd   +26 more
core   +1 more source

Structural and mechanistic basis of capsule O-acetylation in Neisseria meningitidis serogroup A

Nature Communications, 2020
Neisseria meningitidis capsular polysaccharide (CPS) is a major virulence factor and vaccine formulations against Neisseria meningitidis serogroup A (NmA) contain O-acetylated CPS.
Timm Fiebig, Johannes T. Cramer, Andrea Bethe, Petra Baruch, Ute Curth, Jana I. Führing, Falk F. R. Buettner, Ulrich Vogel, Mario Schubert, Roman Fedorov, Martina Mühlenhoff   +10 more
doaj   +1 more source

The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as 'virulence genes' [PDF]

, 2006
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Snyder, Lori A. S., Snyder, Lori AS, Snyder, LA, Saunders Nigel J, Snyder, LAS, Saunders, Nigel, Lori AS Snyder, Saunders, NJ, Nigel J Saunders, Saunders, Nigel J., Snyder Lori AS   +10 more
core   +1 more source

A cross-sectional study assessing the pharyngeal carriage of Neisseria meningitidis in subjects aged 1–24 years in the city of Embu das Artes, São Paulo, Brazil

Brazilian Journal of Infectious Diseases, 2017
Meningococcal carriage is a prerequisite for invasive infection. This cross-sectional study assessed the pharyngeal carriage prevalence in healthy subjects aged 1–24 years in Embu das Artes city, São Paulo, Brazil.
Lily Yin Weckx, Rosana Fiorini Puccini, Antónia Machado, Maria Gisele Gonçalves, Suely Tuboi, Eliana de Barros, Raghavendra Devadiga, Eduardo Ortega-Barria, Romulo Colindres   +8 more
doaj   +1 more source