Results 41 to 50 of about 28,998 (136)

Parental Socio‐Economic Factors and the Risk of Invasive Bacterial Infections in Children: A Register‐Based Finnish Study

Acta Paediatrica, Volume 115, Issue 7, Page 1487-1495, July 2026.
ABSTRACT Aim Little is known about how socio‐economic factors influence severe childhood bacterial infections. We explored whether parental socio‐economic status correlates with the risk of invasive bacterial infections in the offspring. Methods Data on children < 16 years with community‐acquired blood or cerebrospinal fluid culture–positive bacterial ...
Kyrönlahti Anniina, Hermunen Teemu, Nieminen Tea, Koivisto Karoliina, Rantanen Matti, Saxén Harri, Madanat‐Harjuoja Laura   +6 more
wiley   +1 more source

Iptacopan monotherapy resulted in increased hemoglobin level in patients with PNH and hemoglobin ≥10 g/dL after anti‐C5 therapy

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract Patients with paroxysmal nocturnal hemoglobinuria (PNH) on anti‐C5 often experience extravascular hemolysis with anemia. Iptacopan, the first oral proximal complement inhibitor targeting factor B, has shown efficacy and safety in PNH patients. APPULSE‐PNH (NCT05630001), a phase 3b, single‑arm, open‐label trial, enrolled adult patients with PNH
Austin Kulasekararaj, Flore S. de Fontbrune, Anna Gaya, Ilene Weitz, David J. Kuter, Bhumika J. Patel, David J. Araten, Abhay Singh, Jun H. Jang, Richard J. Kelly, Eros Di Bona, Michael Loschi, Vinod Pullarkat, Jörg Schubert, Rosario Notaro, Mustafa N. Yenerel, Joan Beckman, Nicolas Blin, Irina Murakhovskaya, Jens Panse, Eloy Roman, Alexander Röth, Hubert Schrezenmeier, Srinivas Tantravahi, Régis P. de Latour, Navin Mahajan, Luca Monaco, Tao Ding, Tomasz Lawniczek, Philippe Ferber, Marion Dahlke, Antonio M. Risitano   +31 more
wiley   +1 more source

BacSafe: A Comprehensive Database for Integrated Assessment of Bacterial Biosafety

iMetaMed, Volume 2, Issue 2, June 2026.
The substantial threats that bacterial contamination poses to healthcare and industrial production requires a comprehensive assessment of biosafety risks for each bacterial species. Here, we introduce BacSafe, a novel database that integrates diverse domains of biosafety knowledge and evaluates bacterial risk across both clinical and environmental ...
Ye Feng, Chengzhi Liu, Qian Liang, Lupeng Ma, Weilian Chen, Fanyuan Gu, Biao Tang, Zhijian Wang, Guoping Zhao, Huan Chen   +9 more
wiley   +1 more source

Extracellular Vesicles of Giardia duodenalis: Unravelling Their Virulence Factors and Potential to Induce Protection Against Experimental Giardiasis

Journal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) are key mediators of intercellular communication, enabling trans‐kingdom exchange of proteins, nucleic acids, lipids, and metabolites. In Giardia duodenalis, EVs contribute to parasite survival, host–pathogen interactions, and immune modulation.
Corral‐Ruiz Gerardo, Argüello‐García Raúl, Ortiz‐Lozano Dalia, Salazar‐Villatoro Lizbeth, Pech‐Santiago Edar Onam, Espinosa‐Cantellano Martha, Hernández‐Cueto Daniel, Silva‐Olivares D. Angélica, Betanzos Abigail, Ortega‐Pierres M. Guadalupe   +9 more
wiley   +1 more source

PorA typing of Neisseria meningitidis isolates from Iranian children for vaccine design

Vaccine Research, 2018
Introduction: As the causative agent of meningitis, Neisseria meningitidis has different serogroups. The purpose of this study was to investigate the molecular properties of N. meningitidis strains among Iranian cases. Methods: 450 samples were collected
P Afrough, M Vosogh, MR Asadi Karam, A Behrouzi, G Mardani, SD Siadat   +5 more
doaj  

Bacterial antigen detection in cerebrospinal fluid by the latex agglutination test Detecção de antígenos bacterianos no líquido cefalorraquidiano através do teste de aglutinação de latex

Revista do Instituto de Medicina Tropical de São Paulo, 1995
Eighty purulent cerebrospinal fluid (CSF) samples from patients with clinical evidence of meningitis were studied using the Directigen latex agglutination (LA) kit to determine the presence of bacterial antigen in CSF.
Ilka Maria Landgraf, Maria das Graças Adelino Alkmin, Maria de Fátima Paiva Vieira   +2 more
doaj   +1 more source

Lack of association between vaccine‐induced immune thrombocytopenia and thrombosis and HLA loci in a large cohort

British Journal of Haematology, EarlyView.
Linda Schönborn, Ana Tzvetkova, Thomas Thiele, Uwe Völker, Sabine Ameling, Sören Franzenburg, Lars Kaderali, Andreas Greinacher   +7 more
wiley   +1 more source

Hospital‐Associated Antimicrobial Resistant Bacteria on 95 Mobile Phones: An International Metagenomic “Phonome” Analysis

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
On average, phones harbored 3.62 of the top 10 killers and 2.49 ESKAPE organisms. In total, 667 VFGs (8621 Hits) and 262 ARGs (2475 Hits) were identified on 95 mobile phones. Mobile phones serve as a platform for horizontal gene transfer and AMR development.
Adrian Goldsworthy, Matthew Olsen, Nchafatso G. Obonyo, Peter Jones, Simon McKirdy, Abiola Senok, Rashed Alghafri, Rose Ghemrawi, Reem Almheiri, Oystein Tronstad, Jacky Y. Suen, John F. Fraser, Lotti Tajouri   +12 more
wiley   +1 more source

Analysis of the heterogenous structural states of the hexameric ATPase PilU of the type IV pili from Vibrio cholerae

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Type IV pili (T4P) mediate surface motility, host interactions, and DNA uptake through cycles of extension and retraction. While the primary retraction ATPase PilT has been extensively characterized, its homolog PilU remains less well understood despite being demonstrated as a PilT‐dependent retraction ATPase.
Yirui Guo, Shantanu Shukla, George Minasov, Nicole L. Inniss, Thomas Klose, Valerie L. Tokars, Alfonso Mondragón, Zbyszek Otwinowski, Dominika Borek, Karla J. F. Satchell   +9 more
wiley   +1 more source

Frequency of pharyngeal Neisseria Carriage among 10-12 years old pupiles in Tehran, Iran

مجله دانشگاه علوم پزشکی گرگان, 2011
Background and Objective: Neisseria meningitidis is an obligate pathogen of human and temporary colonizes the mucosa of upper respiratory tract. This study was done to determine the frequency of pharyngeal Neisseria Carriage among 10-12 years old pupiles.
Pourmand MR (PhD), Sadighian H (MSc), Abdossamdi Z (MSc), Keshtvarz M (BSc), Mardani N (BSc), Ghoorchian S (BSc), Hadjati M (MD)   +6 more
doaj