Results 61 to 70 of about 61,077 (198)

AustrAIHANZ – consensus guidelines on the investigation and management of autoimmune haemolytic anaemia in Australia and New Zealand

Internal Medicine Journal, EarlyView.
Abstract Autoimmune haemolytic anaemia is a rare immune‐mediated disorder leading to accelerated red cell destruction and anaemia. There is considerable clinical heterogeneity, with some patients barely requiring intervention, while others experience fulminant haemolysis and experience mortality rates as high as 30% with severe anaemia and end‐organ ...
Philip Choi, Eileen Merriman, Ashwini Bennett, Anoop Enjeti, Chee Wee Tan, Isaac Goncalves, Danny Hsu, Jun Yen Ng, Anastazia Keegan, Robert Bird   +9 more
wiley   +1 more source

A systematic review of the diagnostic accuracy of Loop-mediated-isothermal AMPlification (LAMP) in the diagnosis of invasive meningococcal disease in children

BMC Pediatrics, 2019
Background The early recognition of meningococcal disease in children is vital. During the prodrome however, meningococcal infection presents similarly to many self-limiting viral infections. This mandates a cautious approach with many children receiving
Thomas Waterfield, Derek Fairley, Bronagh Blackwood, James McKenna, Michael D. Shields   +4 more
doaj   +1 more source

Improving detection of secondary immunodeficiency and vaccination after invasive airway infections: a prospective cohort study with retrospective comparison

Internal Medicine Journal, EarlyView.
Abstract Background Infections caused by encapsulated pathogens such as Streptococcus pneumoniae, Haemophilus influenzae and Neisseria meningitidis contribute to significant morbidity and mortality, with immunodeficiency being an important risk factor for recurrent and invasive disease.
B. Tan, M. Metlapalli, M. Liu, D. Kotsanas, E. L. Smith, S. Ojaimi   +5 more
wiley   +1 more source

Outbreak of Sexually Transmitted Nongroupable Neisseria meningitidis–Associated Urethritis, Vietnam

Emerging Infectious Diseases, 2023
We report on an outbreak of nongroupable Neisseria meningitidis–associated urethritis, primarily among men who have sex with men in southern Vietnam. Nearly 50% of N. meningitidis isolates were resistant to ciprofloxacin.
Hao Trong Nguyen, Thanh V. Phan, Hau Phuc Tran, Thao Thi Phuong Vu, Nhi Thi Uyen Pham, Tho Thi Thanh Nguyen, Ha Manh Bui, Bao Hac Duong, Thu Nguyen Anh Luu, Nguyen Nhat Pham, Phuc Duy Nguyen, Tu Ngoc Le, Thu Quang Le, Dai Thi Trang Vo, Lan Trong Phan, Nghia Van Khuu, Quang Duy Pham, Thuong Vu Nguyen   +17 more
doaj   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Objectives To critically evaluate the current evidence on microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases, with emphasis on their biological relevance, potential clinical utility, and current translational limitations.
Su Sheng Quach, Ausra Ramanauskaite, Sašo Ivanovski, Pingping Han, Frank Schwarz, Emilio A. Cafferata   +5 more
wiley   +1 more source

Affected Persons in Laboratory Exposures to Human Pathogens and Toxins in Canada, 2016–2024: A Sector‐Specific Analysis

American Journal of Industrial Medicine, Volume 69, Issue 12, Page 1080-1092, December 2026.
ABSTRACT Background Exposures to human pathogens and toxins in licensed facilities in Canada have been monitored by a federal surveillance system since 2015, yet the affected persons (APs) in these incidents remain uncharacterized. This study comprehensively describes APs, highlighting sector‐specific patterns and trends over time.
Emily F. Tran, Christine Abalos, Antoinette N. Davis, Audrey Gauthier, Samuel Bonti‐Ankomah   +4 more
wiley   +1 more source

PorA typing of Neisseria meningitidis isolates from Iranian children for vaccine design

Vaccine Research, 2018
Introduction: As the causative agent of meningitis, Neisseria meningitidis has different serogroups. The purpose of this study was to investigate the molecular properties of N. meningitidis strains among Iranian cases. Methods: 450 samples were collected
P Afrough, M Vosogh, MR Asadi Karam, A Behrouzi, G Mardani, SD Siadat   +5 more
doaj  

Deep learning‐based structure modeling of the Treponema pallidum proteome: Insights into pathogenesis and syphilis vaccine development

Protein Science, Volume 35, Issue 12, December 2026.
Abstract Treponema pallidum ssp. pallidum, the causative agent of syphilis, has a small proteome and encompasses numerous strains. Knowledge gaps remain in understanding the molecular mechanisms of pathogenesis of this bacterium, as well as the structure and function of the full complement of proteins encoded by T. pallidum.
Simon Houston, Steven Marshall, Austin Miller, Aleksander Palkowski, Javier A. Alfaro, Caroline E. Cameron   +5 more
wiley   +1 more source