Results 51 to 60 of about 61,077 (198)

Development of group B meningococcal vaccine: a progress review

Zhongguo gonggong weisheng, 2022
Epidemic cerebrospinal meningitis is a respiratory infectious disease caused by Neisseria meningitidis, most commonly manifesting as meningitis and septicaemia.
Wei ZHAO, Shuang BAI, Yan-li KANG
doaj   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Organism resembling Neisseria gonorrhoeae and Neisseria meningitidis [PDF]

Journal of Clinical Microbiology, 1987
A problem isolate resembling Neisseria gonorrhoeae and Neisseria meningitidis is reported. Growth and biochemical characteristics indicated the organism to be N. meningitidis, whereas serological characteristics indicated it to be N. gonorrhoeae. This vaginal isolate may be a genetically transformed gonococcus with the ability to utilize maltose ...
D S, Hodge, F E, Ashton, R, Terro, A S, Ali   +3 more
openaire   +2 more sources

Host iron binding proteins acting as niche indicators for Neisseria meningitidis [PDF]

, 2009
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited - Copyright ...
Philip W Jordan, Jordan Philip W., Saunders Nigel J., Jordan, PW, Saunders, NJ, Nigel J Saunders   +5 more
core   +2 more sources

Complete Genome Sequence of Serogroup B Neisseria meningitidis Strain C311 [PDF]

, 2021
Neisseria meningitidis strain C311 has been widely used to study meningococcal pathogenesis in the past 30 years, but its genome is not available. Here, we report that the complete C311 genome is 2,311,508 bp in length, contains a total of 2,274 genes ...
Edwards, Jennifer L, Jen, Freda E-C, Atack, John M, Zhang, Yuan, Jennings, Michael P, Freda E.-C. Jen, Jennifer L. Edwards, Michael P. Jennings, John M. Atack, Yuan Zhang   +9 more
core   +1 more source

Variabilidad de las meningoencefalitis bacterianas en el Hospital Pediátrico "Pepe Portilla" Variability of the bacterial meningoencephalitis at "Pepe Portilla" Paediatric Hospital

Revista de Ciencias Médicas de Pinar del Río, 2009
Se realizó un estudio retrospectivo y prospectivo longitudinal de las Meningoencefalitis Bacterianas diagnosticadas en el Hospital Pediátrico "Pepe Portilla" en el año 2006 y 2007, con el objetivo de determinar los gérmenes que han aislado en dicha ...
Maydelin Fernández González, Odalys Padrón González, Dianelis Izquierdo Reina, Lissette Sixto Cordero   +3 more
doaj  

Australian consensus recommendations for the management of increased meningococcal infection risk in adults with neurological diseases treated with complement inhibitors

Internal Medicine Journal, EarlyView.
Abstract Complement inhibitor therapy carries a risk of serious infections, including meningococcal disease. Here we provide evidence‐based recommendations and expert consensus for immunisation and prophylactic treatment of patients receiving, or planning to receive, complement inhibitors for neurological conditions in the Australian setting.
Katherine A. Buzzard, Michael Barnett, Heidi Beadnall, Mirasol Forcadela, Lesley‐Ann Hall, Victoria G. Hall, Todd Hardy, Danny Hsu, Paul Kinsella, Mastura Monif, Sudarshini Ramanathan, Stephen W. Reddel, Sean Riminton, Douglas F. Johnson   +13 more
wiley   +1 more source

The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators [PDF]

, 2009
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in ...
Gilbert, RJ, Saunders, NJ, Sainsbury, S, Owens, RJ, Ren, J, Robinson, CV, Lane, LA, Stuart, DI   +7 more
core   +1 more source

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster, Òscar Vidal‐Gironès, Rowan de Graaf, Ken Kok, Lindsey T. Lelieveld, Jackelien Hoogervorst, Maria J. Ferraz, José Pablo Rivas‐Fernández, Rob F. Lammers, Herman S. Overkleeft, Johannes M. F. G. Aerts, Rolf G. Boot, Carme Rovira, Marta Artola   +13 more
wiley   +2 more sources

Conservation of Meningococcal Antigens in the Genus Neisseria

mBio, 2013
Neisseria meningitidis, one of the major causes of bacterial meningitis and sepsis, is a member of the genus Neisseria, which includes species that colonize the mucosae of many animals.
Alessandro Muzzi, Marirosa Mora, Mariagrazia Pizza, Rino Rappuoli, Claudio Donati   +4 more
doaj   +1 more source