Results 51 to 60 of about 67,546 (282)

First occurrence of the eel parasite Paraquimperia tenerrima in lake Balaton, Hungary [PDF]

, 2006
The parasite fauna of the eel has been studied regularly since the first imported eels were introduced to Lake Balaton in 1963. Over a long period of time no important parasitic infections were recorded. However, the importance of nematode infections has
Székely, Csaba
core  

Modelling the consequences of targeted selective treatment strategies on performance and emergence of anthelmintic resistance amongst grazing calves [PDF]

, 2016
The development of anthelmintic resistance by helminths can be slowed by maintaining refugia on pasture or in untreated hosts. Targeted selective treatments (TST) may achieve this through the treatment only of individuals that would benefit most from ...
Berk, Zoe, Forbes, Andrew B., Kyriazakis, Ilias, Laurenson, Yan C.S.M.   +3 more
core   +2 more sources

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

In vivo and in vitro studies of Cry5B and nicotinic acetylcholine receptor agonist anthelmintics reveal a powerful and unique combination therapy against intestinal nematode parasites. [PDF]

PLoS Neglected Tropical Diseases, 2018
The soil-transmitted nematodes (STNs) or helminths (hookworms, whipworms, large roundworms) infect the intestines of ~1.5 billion of the poorest peoples and are leading causes of morbidity worldwide. Only one class of anthelmintic or anti-nematode drugs,
Yan Hu, Melanie Miller, Bo Zhang, Thanh-Thanh Nguyen, Martin K Nielsen, Raffi V Aroian   +5 more
doaj   +1 more source

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]

, 2015
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
A Tarkowski, AL Moncayo, AM Gan, B Min, Cathy Steel, CH Kuo, CM Steppan, D Artis, D Voehringer, DD Taub, DR Herbert, DR Herbert, DR Neill, Edward J. Pearce, F Chen, Gang Chen, GD Thomas, Graham Le Gros, H Helmby, HK Park, HS Jung, J Bethony, J Urban, J Wang, JA Jackson, Jessica C. Jang, JF Urban Jr, JI Odegaard, JJ Reece, Josiah I. Chung, JT Pesce, K Migita, KT Cuenco, L Boring, L Le Goff, L Patel, LC Osborne, M Lehrke, M Lehrke, M Qatanani, Mali Camberis, Mark A. Barnes, Meera G. Nair, MG Nair, MG Nair, MG Nair, Mitchell A. Lazar, MM Pirvulescu, MP Reilly, N Silswal, P Loke, PF Weller, Philip J. Cooper, PJ George, PJ Hotez, R Anuradha, RM Anthony, RT Semnani, RZ Yang, S Babu, S Babu, S Babu, S Babu, S Jiang, S Lee, Spencer H. Wang, Thomas B. Nutman, TT MacDonald, W He, Y Benomar, YY Hsieh   +70 more
core   +5 more sources

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Helminth and intestinal protozoa infections, multiparasitism and risk factors in Champasack province, Lao People's Democratic Republic.

PLoS Neglected Tropical Diseases, 2011
BackgroundDetailed investigations of multiparasitism are scarce in the Mekong River basin. We assessed helminth (trematode, nematode, and cestode), and intestinal protozoa infections, and multiparasitism in random population samples from three different ...
Somphou Sayasone, Tippi K Mak, Monely Vanmany, Oroth Rasphone, Penelope Vounatsou, Jürg Utzinger, Kongsap Akkhavong, Peter Odermatt   +7 more
doaj   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Helminth Infections: Recognition and Modulation of the Immune Response by Innate Immune Cells [PDF]

, 2018
The survival of helminths in the host over long periods of time is the result of a process of adaptation or dynamic co-evolution between the host and the parasite. However, infection with helminth parasites causes damage to the host tissues producing the
Ambrosio, Laura Fernanda, Celias, Daiana Pamela, Cervi, Laura Alejandra, Chiapello, Laura Silvina, Motran, Claudia Cristina, Silvane, Leonardo Micael, Theumer, Martín Gustavo, Volpini, Ximena   +7 more
core   +1 more source