Results 61 to 70 of about 906,900 (290)

Discovery of novel inhibitors targeting nematode chitinase CeCht1: Virtual screening, biological evaluation, and molecular dynamics simulation

Frontiers in Chemistry, 2022
Plant-parasitic nematodes are a main limiting factor for worldwide agriculture. To reduce the global burden of nematode infections, chemical nematicides are still the most effective methods to manage nematodes. With the increasing resistance of nematodes,
Shengqiang Shen, Baokang Ding, Xi Jiang, Xi Jiang, Meiling Yang, Qing Yang, Qing Yang, Lili Dong   +7 more
doaj   +1 more source

Diversity in parasitic nematode genomes: the microRNAs of Brugia pahangi and Haemonchus contortus are largely novel [PDF]

, 2012
<b>BACKGROUND:</b> MicroRNAs (miRNAs) play key roles in regulating post-transcriptional gene expression and are essential for development in the free-living nematode Caenorhabditis elegans and in higher organisms.
Winter, A.D., Weir, W., Hunt Martin, Gilleard, J.S., Berriman, M., Devaney, E., Collette Britton, Alan D Winter, Gilleard John S, Britton Collette, Winter Alan D, Martin Hunt, Hunt, M., Devaney Eileen, Britton, C., Matthew Berriman, Eileen Devaney, John S Gilleard, Weir William, Berriman Matthew, William Weir   +20 more
core   +1 more source

A rhesus macaque model of α‐dystroglycanopathy caused by a POMT1 splice altering variant

Animal Models and Experimental Medicine, EarlyView.
Rhesus macaques homozygous for a naturally occurring spice altering variant in the POMT1 gene develop lissencephaly, microphthalmia, and muscular contracture. The presentation models severe presentation of the human Walker‐Warburg syndrome. Abstract Background Biallelic mutations in genes associated with α‐dystroglycan glycosylation manifest in a ...
Anya Nordlund, Brian LaMendola, Nathan P. Crilly, Seth Kittle, Betsy M. Ferguson, Anne D. Lewis, Jeff Wall, Samuel M. Peterson   +7 more
wiley   +1 more source

Domestication of ruminant livestock and the impact of nematode parasites:possible implications for the reindeer industry

Rangifer, 2005
In a balanced ecological system, both host and nematode parasite populations are firmly controlled by a complex array of interacting factors. However domestication of livestock has tipped the balance in favour of the parasites.
Peter J. Waller
doaj   +1 more source

Development of an educational cartoon to prevent worm infections in Chinese schoolchildren [PDF]

, 2013
Background: With more than two billion people infected worldwide, soil-transmitted helminths (STH) are the most widespread infections. To date, STH control efforts rely predominantly on recurrent mass drug administration (MDA), which does not prevent ...
Guo, Feng-Ying, Yuan, Li-Ping, Li-Ping Yuan, Robert S Li, Li, Robert S., Li, Robert S, McManus, Donald P, Yue-Sheng Li, Sheng-Ming Li, Feng-Ying Guo, Bedford, Andrew, Franziska A Bieri, Williams, Gail M., Yong-Kang He, Williams, Gail, Gray, Darren J., Li, Yue-Sheng, Giovanna Raso, McManus, Donald P., Raso, Giovanna, Andrew Bedford, Donald P McManus, Gray, Darren, Bieri, Franziska A, Darren J Gray, He, Yong-Kang, Gail M Williams, Bieri, Franziska A., Li, Sheng-Ming   +28 more
core   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Benzimidazole Resistance in Cattle: The First Report of the Presence of F200Y Mutation in Cooperia in Ecuador

Veterinary Sciences, 2023
Anthelmintic resistance among GINs in cattle is a worldwide issue. Identifying the early signs of anthelmintic resistance (AR) is necessary to sustainably manage bovine parasitic infections.
Pamela Vinueza, Marlon Calispa, Luis Condolo, Paula Toalombo, Peter Geldhof   +4 more
doaj   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Abundant variation in microsatellites of the parasitic nematode Trichostrongylus tenuis and linkage to a tandem repeat [PDF]

, 2006
An understanding of how genes move between and within populations of parasitic nematodes is important in combating the evolution and spread of anthelmintic resistance.
Dawson, D.A., Adam, Aileen, Adam, A., Buckland, R, Keller, L F, Johnson, P.C.D., Johnson, Paul C D, Dawson, Deborah A, Webster, L M I, Webster, L.M.I., Buckland, R., Keller, Lukas F, Johnson, P C D, Dawson, D A, Webster, Lucy M I, Keller, L.F., Adam, A, Buckland, Robert   +17 more
core   +1 more source

Dynamics of biotic resistance to plant invasions

Biological Reviews, EarlyView.
ABSTRACT Biotic resistance, the reduction in invasion success caused by native communities, plays an important role in the long‐term dynamics of biological invasions. A large body of empirical research on biotic resistance has accumulated since the last comprehensive review on the subject 20 years ago, enabling us to achieve a refined understanding of ...
Christine S. Sheppard, Joshua I. Brian, Wayne Dawson, Petr Dostál, Franz Essl, Michal Gruntman, Tina Heger, Mark van Kleunen, Mialy Razanajatovo, Lena C. Reimann, Frank M. Schurr, Montserrat Vilà, Florencia A. Yannelli, Marina Golivets   +13 more
wiley   +1 more source