Results 91 to 100 of about 4,565 (205)
Antibiotics alter development and gene expression in the model cnidarian Nematostella vectensis
Background Antibiotics are commonly used for controlling microbial growth in diseased organisms. However, antibiotic treatments during early developmental stages can have negative impacts on development and physiology that could offset the positive ...
Quinton Krueger, B. Phippen, A. Reitzel
semanticscholar +1 more source
Structural Basis of GABAB Receptor Activation during Evolution
This study explores the structural and functional mechanisms of the drosophila GABAB receptor, a key role in neurotransmission. Using cryo‐EM, the research reveals how the receptor's activation differs from its human counterpart, highlighting unique evolutionary features.
Guofei Hou +14 more
wiley +1 more source
Regulation ofNematostellaneural progenitors by SoxB, Notch and bHLH genes [PDF]
Notch signalling, SoxB and Group A bHLH ‘proneural’ genes are conserved regulators of the neurogenic program in many bilaterians. However, the ancestry of their functions and interactions is not well understood. We address this question in the sea anemone Nematostella vectensis, a representative of the Cnidaria, the sister clade to the Bilateria.
Richards, Gemma Sian, Rentzsch, Fabian
openaire +5 more sources
Axis Patterning by BMPs: Cnidarian Network Reveals Evolutionary Constraints
BMP signaling plays a crucial role in the establishment of the dorso-ventral body axis in bilaterally symmetric animals. However, the topologies of the bone morphogenetic protein (BMP) signaling networks vary drastically in different animal groups ...
Grigory Genikhovich +8 more
doaj +1 more source
Gastrulation in the cnidarian Nematostella vectensis occurs via invagination not ingression
Gastrulation is a central event in metazoan development, involving many cellular behaviors including invagination, delamination, and ingression. Understanding the cell biology underlying gastrulation in many different taxa will help clarify the evolution of gastrulation mechanisms. Gastrulation in the anthozoan cnidarian Nematostella vectensis has been
Magie, Craig R. +2 more
openaire +2 more sources
Bilaterian animals have evolved complex sensory organs comprised of distinct cell types that function coordinately to sense the environment. Each sensory unit has a defined architecture built from component cell types, including sensory cells, non ...
Keith Z. Sabin +12 more
semanticscholar +1 more source
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 5, Page 378-382, July 2026.
Mark Rebeiz +9 more
wiley +1 more source
Reduced Adult Neurogenesis in Humans Results From a Tradeoff Rather Than Direct Negative Selection
Embryonic radial glia (RG) generate neurons, glial cells, and later adult neural stem cells, which sustain adult neurogenesis (top, left to right). Human‐specific genetic modifications (blue arrow), selected to boost early RG neurogenic activity, may lead to premature RG exhaustion and reduced adult neurogenesis in the human brain (bottom).
David Morizet, Laure Bally‐Cuif
wiley +1 more source
Unravelling the developmental and functional significance of an ancient Argonaute duplication
The sea anemone Nematostella vectensis expresses miRNAs and two Argonaute (AGO) proteins. Here the authors show that NveAGO1 and NveAGO2 are loaded with overlapping but different sets of miRNAs and that NveAGO2 binds both miRNAs and endo-siRNAs. Both AGO
Arie Fridrich +4 more
doaj +1 more source
Abstract Background The emergence of multicellularity in animals marks a pivotal evolutionary event, which was likely enabled by molecular innovations in the way cells adhere and communicate with one another. β‐Catenin is significant to this transition due to its dual role as both a structural component in the cadherin–catenin complex and as a ...
Brian M. Walters +5 more
wiley +1 more source

