Results 91 to 100 of about 209,106 (262)

Editorial: Improving surgical outcomes after pancreatic resection

Frontiers in Oncology, 2022
Damiano Caputo, Damiano Caputo, Mark Girgis   +2 more
doaj   +1 more source

Survival analysis stratified by neoadjuvant chemotherapy regimen.

, 2021
(A) Kaplan-Meier curves for overall survival stratified by neoadjuvant chemotherapy regimen. (B) Kaplan-Meier curves for cancer specific survival stratified by neoadjuvant chemotherapy regimen.
Artur Lemiński (11642863), Tomasz Byrski (11642869), Krystian Kaczmarek (11642866), Marcin Słojewski (204584)   +3 more
core   +1 more source

Radiation‐Triggered Chemokine‐Secreting Probiotics for Boron Neutron Capture Therapy Based Radioimmunotherapy

Advanced Science, EarlyView.
Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu, Yuzhong Qian, Shaobo Huang, Bingbing Li, Yue Yu, Xiang Cheng, Chang Chen, Jiheng Wang, Maosong Yang, Lizheng Liang, Xiancai Meng, Zhigang Liu   +11 more
wiley   +1 more source

Neoadjuvant everolimus in renal angiomyolipoma with or without tuberous sclerosis complex: Results from a multicenter, retrospective study

Cancer Medicine
Objectives To assess the efficacy and safety of preoperative neoadjuvant everolimus in renal angiomyolipomas (AML) patients with or without Tuberous Sclerosis Complex (TSC).
Ruopeng Su, Tingxuan Huang, Liangyou Gu, Yige Bao, Zhihong Liu, Pinghong Dao, Lin Yao, Xiaoyi Hu, Guanghou Fu, Jitao Wu, Thibault Tricard, Guangyu Wu, Minfeng Chen, Chancan Li, Zhiyang Huang, Bing Zheng, Yonghui Chen, Wei Xue, Gang Guo, Pei Dong, Jiwei Huang, Jin Zhang   +21 more
doaj   +1 more source

Ribonucleotides Amplify Mitochondrial DNA‐Driven cGAS–STING Activation via FdUMP‐ribonucleotide Hybrid Particles to Potentiate Chemoimmunotherapy

Advanced Science, EarlyView.
This work develops a metabolic sharing strategy that employs cytidine monophosphate (CMP) to competitively reprogram floxuridine (FUDR) pyrimidine metabolism in colorectal tumor cells. Elevated intracellular FdUMP induces nucleotide imbalance, drives mitochondrial DNA release and cGAS‐STING innate immune cascade activation, and potentiates robust ...
Chao Wang, Chenxuan Zhao, Yesong Yao, Zhiwen Zou, Anxin Shi, Zhuo Feng, Mingkang Yang, Yue Yu, Yang Liu, Xuehui Rui, Jinhui Wu   +10 more
wiley   +1 more source

Neoadjuvant Treatment Is Not Associated with Better Survival in T4 Non-Small Cell Lung Cancer

Objective: The best treatment strategy for T4 non-small cell lung cancer (NSCLC) has yet to be defined. However, studies have shown that surgical resection benefits selected patients without N2/N3 disease.
Gizem Özçıbık Işık, İsmail Sarbay, Akif Turna, Ezel Erşen, H. Volkan Kara, Burcu Kılıç, Halil İbrahim Bulut, M. Kamil Kaynak   +7 more
core   +1 more source

Neoadjuvant Therapy in Colon Cancer [PDF]

Neoadjuvant therapy in colon cancer, traditionally reserved for rectal cancer, is gaining traction as a promising treatment strategy. This chapter offers a concise overview of neoadjuvant therapy in colon cancer, highlighting its evolving role, benefits,
Beets, Geerard L.
core   +1 more source

Radio-chemotherapy as a preoperative treatment for advanced rectal cancer. Evaluation of down-staging and morbidity [PDF]

, 2002
Background: The standard therapy for patients with clinically resectable rectal cancer is generally considered to be surgery, If the patient is diagnosed with advanced disease, postoperative radiochemotherapy (RCT) is usually recommended. In our study we
Wilkowski, R., Schaffer, Pamela Manuela, Thoma, M., Dühmke, Eckhart, Schaffer, Moshe   +4 more
core   +1 more source

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

Advanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang, Shilong Wang, Meng Wang, Ruixian Yu, Jingwu Yue, Lin Shao, Hui Zhang, Mengwen Zhu, Luyang Tian, Shuting Cheng, Weimin Qin, Yang Tang, Yi Han, Wenjia Wang, Liwei An, Yan Meng, Shi Jiao, Zhaocai Zhou   +17 more
wiley   +1 more source

Neoadjuvant-Based Triple Therapy for Hepatocellular Carcinoma with Type I/II Portal Vein Tumor Thrombosis [PDF]

Guimin Hou,1,* Feng Zhang,1,* Xielin Feng,1 Yan Chen,2 Jinliang Zhang,1 Haiqing Wang1 1Department of Hepatopancreatobiliary Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital and Institute, Affiliated Cancer Hospital of
Zhang F, Zhang J, Feng X, Chen Y, Wang H, Hou G   +5 more
core