Results 41 to 50 of about 209,106 (262)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Neoadjuvant osimertinib and chemotherapy for stage IIIA primary pulmonary carcinosarcoma with EGFR 19DEL mutation: A case report

Frontiers in Oncology, 2023
Epidermal growth factor receptor (EGFR) mutations have been frequently detected in patients with pulmonary adenocarcinoma. EGFR Exon 19Del and 21L858R mutations are the two most common EGFR mutations.
Hongming Wang, Zhijun Wu, Yangfeng Du, Tao Wu, Wei Tian, Wen Dong, Juan Cai, Jiang Zheng, Yan Zhang, Shiyan Li, Wei Xu, Jing Qin, Zemin Xiao   +12 more
doaj   +1 more source

Change of Fagotti score is associated with outcome after neoadjuvant chemotherapy for ovarian cancer. [PDF]

, 2023
OBJECTIVE To investigate whether a change in the Fagotti score (ΔFagotti) following neoadjuvant chemotherapy is predictive of resection to no residual disease (R0) and survival in women diagnosed with ovarian cancer.
Ruggeri, Giovanni, Mueller, Michael D, Siegenthaler, Franziska, Wampfler, Julian, Saner, Flurina Anna-Carina Maria, Imboden, Sara   +5 more
core   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Impacts of Neoadjuvant Hormonal Therapy Prior to Robot-Assisted Radical Prostatectomy on Postoperative Hormonal- and Sexual-Related Quality of Life – Assessment by Patient-Reported Questionnaire

Research and Reports in Urology, 2022
Soichiro Ogawa,1 Akihisa Hasegawa,1 Shunta Makabe,1 Akifumi Onagi,1 Kanako Matsuoka,1 Emina Kayama,1 Tomoyuki Koguchi,1 Junya Hata,1 Yuichi Sato,1 Hidenori Akaihata,1 Masao Kataoka,1 Nobuhiro Haga,2 Yoshiyuki Kojima1 1Department of Urology, Fukushima ...
Ogawa S, Hasegawa A, Makabe S, Onagi A, Matsuoka K, Kayama E, Koguchi T, Hata J, Sato Y, Akaihata H, Kataoka M, Haga N, Kojima Y   +12 more
doaj  

Neoadjuvant Four-Drug Combination Therapy for NSCLC With EGFR Mutation Avoiding Total Pneumonectomy

Frontiers in Oncology, 2020
We report a case of successful neoadjuvant four-drug combination therapy to avoid total pneumonectomy. A 33-year-old male patient was diagnosed with locally advanced non-squamous NSCLC harboring EGFR mutation in the left lower lobe.
Jingpei Li, Jingpei Li, Jingpei Li, Ke Xu, Ke Xu, Ke Xu, Weipeng Cai, Weipeng Cai, Weipeng Cai, Yalei Zhang, Yalei Zhang, Yalei Zhang, Xin Zeng, Fei Cui, Fei Cui, Fei Cui, Zhexue Hao, Zhexue Hao, Zhexue Hao, Jun Liu, Jun Liu, Jun Liu, Jianxing He, Jianxing He, Jianxing He   +24 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Neoadjuvant lenvatinib for inoperable thyroid cancer: A case report and literature review

Cancer Reports, 2022
Background Poorly differentiated thyroid cancer (PDTC) is now classified as a separate thyroid tumor entity. It has male predominance and poor prognosis compared to differentiated TC. Case We report a case of a patient with PDTC who was previously deemed
Khalid Alshehri, Yousuf Alqurashi, Mazin Merdad, Shaza Samargandy, Razan Daghistani, Hani Marzouki   +5 more
doaj   +1 more source

Relevance of Pathological Complete Response after Neoadjuvant Therapy for Breast Cancer

, 2016
Breast cancer is a heterogeneous disease, and the different biological subtypes have different prognostic impacts. Neoadjuvant trials have recently become popular as they offer several advantages compared to traditional adjuvant trials.
Angela Pennisi, Thomas Kieber-Emmons, Issam Makhoul, Laura Hutchins, Angela Pennisi   +4 more
core   +1 more source

Phase II trial of preoperative radiochemotherapy with concurrent bevacizumab, capecitabine and oxaliplatin in patients with locally advanced rectal cancer [PDF]

, 2013
Background: Preoperative radiochemotherapy (RCT) with 5-FU or capecitabine is the standard of care for patients with locally advanced rectal cancer (LARC). Preoperative RCT achieves pathological complete response rates (pCR) of 10-15%.
Erik Engel, Engel, Erik, Jürgen Dunst, Florian Würschmidt, Kathrin Dellas, Arnold, Dirk, Dirk Arnold, Michael Richter, Richter, Michael, Rödel, Claus, Thomas Reese, Höhler, Thomas, Thomas Höhler, Claus Rödel, Dellas, Kathrin, Reese, Thomas, Wagner, Wolfgang, Dunst, Jürgen, Würschmidt, Florian, Wolfgang Wagner   +19 more
core   +1 more source