Results 121 to 130 of about 150,246 (305)

Neoadjuvant chemotherapy in oesophageal cancer

, 2009
Neoadjuvant chemotherapy in oesophageal cancer has gained rapid favour in le United Kingdom over the past few years. It remains controversial outside the UK, with mixed results from clinical trials.
Sujendran, Vijay
core  

Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures

, 2011
Background: Current prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers.
Pusztai, Lajos, Lajos Pusztai, Schmidt Marcus, Karn, Thomas, Lars Hanker, Holtrich Uwe, Ruckhäberle Eugen, Volkmar Müller, Liedtke, Cornelia, Karn Thomas, Shiang Christine Y., Rody Achim, Gätje, Regine, Solbach Christine, Eugen Ruckhäberle, Pusztai Lajos, Müller, Volkmar, Cornelia Liedtke, Rody, Achim, Ahr Andre, Ruckhäberle, Eugen, Marcus Schmidt, Christine Y Shiang, Solbach, Christine, Gaetje Regine, Ahr, André, Andre Ahr, Thomas Karn, Hanker Lars, Achim Rody, Schmidt, Marcus, Shiang, Christine Y., Hanker, Lars, Takayuki Iwamoto, Holtrich, Uwe, Iwamoto Takayuki, Manfred Kaufmann, Liedtke Cornelia, Uwe Holtrich, Christine Solbach, Müller Volkmar, Iwamoto, Takayuki, Kaufmann Manfred, Kaufmann, Manfred, Regine Gaetje   +44 more
core   +1 more source

Predicting the Efficacy of Adjuvant Chemotherapy Using Immuno‐Nutritional and Inflammatory Markers in Elderly Patients With Stage III Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to determine whether immuno‐nutritional and inflammatory markers could serve as predictors of the outcomes of postoperative adjuvant chemotherapy for stage III colorectal cancer in elderly patients. Postoperative lymphocyte‐to‐monocyte ratio and postoperative C‐reactive protein‐to‐albumin ratio accurately predicted the efficacy of ...
Tomoya Tago, Yasuyuki Takamizawa, Takeharu Kato, Hiroshi Nagata, Konosuke Moritani, Shunsuke Tsukamoto, Yukihide Kanemitsu   +6 more
wiley   +1 more source

A microscopically assisted limited colectomy mouse model of early colon cancer

Animal Models and Experimental Medicine, EarlyView.
Establishment, surgery, and evaluation process of a microscope‐assisted limited colon resection mouse model for early‐stage colon cancer. Abstract Background Currently, there is a lack of an adequate rodent model for investigating surgical techniques and comprehensive treatment options for patients with colorectal cancer (CRC).
Yu Han, Yixin Zhang, Dazhi Gao, Xuefeng Zhao   +3 more
wiley   +1 more source

Serum miR-4530 sensitizes breast cancer to neoadjuvant chemotherapy by suppressing RUNX2

, 2018
Xiao-Xiao Wang,1,* Fu-Gui Ye,2,* Jie Zhang,1,* Jun-Jing Li,1 Qing-Xia Chen,1 Pei-Yang Lin,1 Chuan-Gui Song1 1Department of Breast Surgery, Affiliated Union Hospital, Fujian Medical University, Fuzhou, People’s Republic of China; 2Department of ...
Ye FG, Chen QX, Lin PY, Song CG, Zhang J, Wang XX, Li JJ   +6 more
core  

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

Advanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira, Patrick Opdensteinen, Andrea Simms, Seongwon Jung, Giuliana P. Mognol, Hui Chen, Judith A. Varner, Nicole F. Steinmetz   +7 more
wiley   +1 more source

Neoadjuvant chemotherapy among patients treated for nonmetastatic breast cancer in a population with a high HIV prevalence in Johannesburg, South Africa

, 2018
Paul Ruff,1,2 Herbert Cubasch,2,3 Maureen Joffe,2,4 Evan Rosenbaum,5 Nivashni Murugan,2,3 Ming-Chih Tsai,2,3 Oluwatosin Ayeni,2 Katherine D Crew,5–7 Judith S Jacobson,6,7 Alfred I Neugut5–7 1Division of Medical Oncology, Department of ...
Tsai MC, Cubasch H, Jacobson JS, Murugan N, Neugut AI, Ayeni O, Crew KD, Rosenbaum E, Joffe M, Ruff P   +9 more
core  

Pharmacogenomic profiling of the efficacy of gemcitabine monotherapy in metastatic pancreatic cancer: Subgroup analysis of the GENESECT study

British Journal of Clinical Pharmacology, EarlyView.
Aim In the GENESECT study, no significant gemcitabine (GEM) metabolism‐related germline genetic polymorphisms (GPs) were identified because approximately 70% of patients received combination therapy with nab‐paclitaxel, which has metabolic pathways different from GEM.
Takashi Yokokawa, Daiki Tsuji, Masahiro Hatori, Kazuyoshi Kawakami, Masahiko Nakao, Takuya Yano, Yuichiro Arakawa, Keisuke Matsuo, Yasukata Ohashi, Masato Ozaka, Naoki Sasahira, Yasuhiko Sakata, Yuki Kogure, Shinya Tamaki, Atsushi Wada, Yusuke Taki, Wataru Suzuki, Kazuo Kobayashi, Hiroshi Ishii, Kunihiko Itoh, Masakazu Yamaguchi, Kenichi Suzuki   +21 more
wiley   +1 more source

Cost-effectiveness of perioperative durvalumab plus neoadjuvant chemotherapy for muscle invasive bladder cancer in the United States

Therapeutic Advances in Medical Oncology
Background: The management of muscle-invasive bladder cancer (MIBC) remains challenging. The phase III NIAGARA trial showed that adding durvalumab to neoadjuvant chemotherapy significantly enhances event-free and overall survival for MIBC patients ...
Caicong You, Jiahao Zhang, Jianying Lei, Wu Fu, Maobai Liu, Hongfu Cai, Bin Zheng, Na Li   +7 more
doaj   +1 more source

Efficacy of neoadjuvant platinum-based chemotherapy during the second and third trimester of pregnancy in women with cervical cancer: an updated systematic review and meta-analysis

, 2018
Yizuo Song, Yi Liu, Min Lin, Bo Sheng, Xueqiong Zhu Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China Purpose: To evaluate the efficacy and safety of neoadjuvant platinum-based ...
Liu Y, Zhu X, Sheng B, Lin M, Song Y
core