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Neoadjuvant Chemotherapy for Nonmetastatic Osteosarcoma of the Extremities
Clinical Orthopaedics and Related Research, 1991Between September 1986 and December 1988, 125 patients with osteosarcoma of the extremities entered the second neoadjuvant study at the authors' institution. Patients received preoperatively two cycles of methotrexate (MTX) intravenously, followed by cisplatinum (CDP) intraarterially, plus adriamycin (ADM) intravenously.
BACCI G +15 more
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NEOADJUVANT CHEMOTHERAPY IN GYNECOLOGIC ONCOLOGY
Surgical Clinics of North America, 2001The use of neoadjuvant chemotherapy in conjunction with surgery in squamous carcinoma of the uterine cervix can reduce the surgical treatment extent (to be confirmed) in small-volume tumors (diameter < 4 cm) and increase overall survival and disease-free interval in localized median-volume tumors (< or = 8 cm) and improve the quality of life of ...
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Neoadjuvant chemotherapy in cervix cancer
1994Despite the decrease in the incidence of cervix cancer over the last decade, 13 500 new cases and 4400 deaths were expected in the United States in 1992 [1]. Accessibility of the cervix for cytologic evaluation via the Pap smear, visual inspection by colposcopy, and histologic evaluation by biopsy have made cervical cacer a preventable and potentially ...
P R, Dottino, R A, Segna
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Neoadjuvant chemotherapy in cervical cancer: an update
Expert Review of Anticancer Therapy, 2015The role of neoadjuvant chemotherapy (NACT) has been investigated in order to improve prognosis of patients with locally advanced cervical cancer. According to a meta-analysis, NACT followed by radiotherapy may be detrimental with a low dose of cisplatin and longer cycle intervals.
LAPRESA, MARIATERESA +3 more
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Benefits of Neoadjuvant Chemotherapy in NSCLC
Chest, 1996There is a significant potential benefit for induction chemotherapy in the management of non-small cell lung cancer (NSCLC). The real extent of such benefit is difficult to assess on the basis of available data owing to the intrinsic limitations of phase II studies.
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Neoadjuvant chemotherapy and ongoing-trials.
Annali italiani di chirurgia, 2011The history of preoperative therapy for gastric carcinoma was outlined here to demonstrate its value in terms of safety and efficacy.The data collected in this review were obtained from studies found in PubMed using the search terms "preoperative chemotherapy", "preoperative radiotherapy", "preoperative chemoradiotherapy", "neoadjuvant treatment", and
D'Ugo, Domenico, Biondi, Alberto
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Neoadjuvant Chemotherapy and Biomarkers
2020Neoadjuvant or presurgical therapy refers to the administration of therapy before surgery and has been used for over two decades to downstage locally advanced and unresectable primary breast cancers to make them operable. The goal of neoadjuvant therapy is to improve surgical outcomes by causing tumor shrinkage by providing effective systemic therapy ...
Niketa Chotai, Supriya Kulkarni
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Neoadjuvant chemotherapy for cervical cancer
Expert Opinion on Pharmacotherapy, 2003None of the current surgical or radiation treatment strategies for cervical cancer satisfactorily leads to a high disease-free survival and a low risk for treatment-related complications in patients with bulky or locally-advanced disease. Neoadjuvant chemotherapy (NACT) prior to surgery or radiation therapy has been studied as a means to reduce tumour ...
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Preoperative (Neoadjuvant) Chemotherapy
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1986Clinical and Scientific Considerations in Preoperative (Neoadjuvant) Chemotherapy.- Experimental Adjuvant Chemotherapy: An Overview.- Theoretical Considerations Regarding the Early Use of Adjuvant Chemotherapy.- Experimental Preoperative Chemotherapy.- Implications of Certain Cell Kinetic and Biological Parameters for Preoperative Chemotherapy ...
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