Results 151 to 160 of about 4,626,170 (385)
Analysis of pathological remission degree and influencing factors of radical surgery after neoadjuvant immunotherapy combined with chemotherapy in patients with locally advanced esophageal squamous cell carcinoma [PDF]
Zhongguo aizheng zazhiBackground and purpose: Radical surgery after neoadjuvant immunotherapy combined with chemotherapy (nICT) in patients with locally advanced esophageal squamous cell carcinoma (LAESCC) has good efficacy and safety, and it can improve the patients ...
LIAO Ziyi, PENG Yang, ZENG Beilei, MA Yingying, ZENG Li, GAN Kelun, MA Daiyuan
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JAMA Oncology, 2018 Importance Patients with borderline-resectable pancreatic ductal adenocarcinoma have historically poor outcomes with surgery followed by adjuvant chemotherapy. Evaluation of a total neoadjuvant approach with highly active therapy is warranted.
Janet E. Murphy +17 more
semanticscholar +1 more source
Annals of Gastroenterological Surgery, EarlyView.This study investigated the utility of the Japanese NCD risk calculator for preoperative assessment in elderly patients undergoing pancreaticoduodenectomy (PD), using a validation study design. In the training cohort, two preoperative factors—the predicted incidence of postoperative ADL decline ≥ 44.8% and Clavien–Dindo grade IV or higher complications
Nana Kimura +9 more
wiley +1 more source
Journal of Clinical Oncology, 2018 PURPOSE To determine the activity of pembrolizumab as neoadjuvant immunotherapy before radical cystectomy (RC) for muscle-invasive bladder carcinoma (MIBC) for which standard cisplatin-based chemotherapy is poorly used. PATIENTS AND METHODS In the PURE-
A. Necchi +22 more
semanticscholar +1 more source
Annals of Gastroenterological Surgery, EarlyView.This study investigated the association between radiographic and pathological response assessments among patients with pancreatic cancer receiving neoadjuvant chemotherapy and neoadjuvant chemoradiotherapy. The present study revealed that discrepancies between radiographic and histological responses may differ according to the type of therapy ...
Satoru Miyahara +8 more
wiley +1 more source
Prediction of Treatment Response to Neoadjuvant Chemotherapy for Breast Cancer via Early Changes in Tumor Heterogeneity Captured by DCE-MRI Registration. [PDF]
, 2019 We analyzed DCE-MR images from 132 women with locally advanced breast cancer from the I-SPY1 trial to evaluate changes of intra-tumor heterogeneity for augmenting early prediction of pathologic complete response (pCR) and recurrence-free survival (RFS ...
Cohen, Eric +8 more
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Neoadjuvant therapy for ovarian cancer
Chinese Clinical Oncology, 2018 Ovarian cancer (OC) is a common oncological disease, which affects approximately 1.5% of women and holds the first position in the structure of gynecological cancer mortality.
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Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background Neoadjuvant chemotherapy (NAC) has been extensively developed for locally advanced gastric cancer (GC). In Asia, S‐1‐based regimens, such as docetaxel, oxaliplatin, and S‐1 (DOS) and S‐1 and oxaliplatin (SOX), are expected to become the standard of care.
Kota Kawabata +9 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.This study evaluated the prognostic impact of arterial contact angle in patients with borderline resectable pancreatic cancer undergoing neoadjuvant therapy and surgery. An arterial contact angle of ≥ 90° was associated with higher R1 resection rates and worse survival outcomes.
Katsuhisa Ohgi +8 more
wiley +1 more source
Advances for achieving a pathological complete response for rectal cancer after neoadjuvant therapy
Chronic Diseases and Translational Medicine, 2016 Neoadjuvant therapy has become the standard of care for locally advanced mid-low rectal cancer. Pathological complete response (pCR) can be achieved in 12%â38% of patients. Patients with pCR have the most favorable long-term outcomes.
Jian Cui +4 more
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