Results 151 to 160 of about 4,732,777 (361)

Total Neoadjuvant Therapy for Rectal Cancer: Why Japan Says “Not Yet”

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Total neoadjuvant therapy (TNT) has rapidly gained global acceptance as a standard treatment for locally advanced rectal cancer (LARC). Supported by multiple phase III trials, TNT improves pathological complete response (pCR) rates, enhances systemic control, and expands opportunities for non‐operative management (NOM).
Kay Uehara, Akihisa Matsuda, Takeshi Yamada, Aitsariya Monkhonsupphawan, Hiroshi Yoshida   +4 more
wiley   +1 more source

Impact of Renin‐Angiotensin System Inhibitors on Renal Function During Temporary Ileostomy Period in Rectal Cancer Patients: A Retrospective Cohort Study

Annals of Gastroenterological Surgery, EarlyView.
This retrospective study explored the potential impact of renin–angiotensin system inhibitors (RASIs) on renal function during the ileostomy period in patients undergoing rectal cancer surgery. RASI use was associated with early postoperative renal impairment, and relatively slow recovery of renal function was observed until stoma closure.
Yusaku Shogen, Ryo Seishima, Masayoshi Monno, Satoru Morita, Kohei Shigeta, Koji Okabayashi, Yuko Kitagawa   +6 more
wiley   +1 more source

A study on the impact of neoadjuvant therapy on molecular subtype conversion in breast cancer

World Journal of Surgical Oncology
Purpose The aim of this study was to examine molecular subtype conversions in patients who received neoadjuvant therapy. Methods and materials A retrospective analysis was performed on 316 patients who underwent neoadjuvant therapy at Zhongnan Hospital ...
Run-Ze Zhang, Dong Liu, Yuan Ke, Wen-Qi Cai, Lin-Hui Zheng, Chao-Yan Wu, Hai-Jun Yu   +6 more
doaj   +1 more source

Controversies and Perspectives in the Current Management of Patients with Locally Advanced Rectal Cancer—A Systematic Review

Life
Traditionally, the therapeutic approach to rectal cancer has involved neoadjuvant chemoradiotherapy followed by surgical resection, and, in some cases, adjuvant chemotherapy.
Roxana Elena Stefan, Rodica Daniela Birla, Mircea Gheorghe, Daniela Elena Dinu, Petre Angel Hoara, Diana Ciuc, Valeriu-Gabi Dinca, Silviu Constantinoiu   +7 more
doaj   +1 more source

Endostatin neoadjuvant gene therapy extends survival in an orthotopic metastatic mouse model of renal cell carcinoma

, 2011
Marina de Souza Braga, Karen Barbosa Chaves, Roger Chammas, Nestor Schor, Maria Helena Bellini   +4 more
openalex   +1 more source

522 UNDER-UTILIZATION OF NEOADJUVANT THERAPY FOR ELDERLY PATIENTS WITH LOCALLY ADVANCED GASTRIC CANCER [PDF]

, 2023
Julia M. Greene, Sean Nassoiy, Jessica Weiss, Stephanie Ming Young, Daniel P. Milgrom, Douglas Hanes, Melanie Goldfarb   +6 more
openalex   +1 more source

Exercise and Nutrition Prehabilitation Program During Preoperative Chemotherapy Followed by Esophagectomy in Older Patients With Esophageal Cancer: A Randomized Clinical Trial

Annals of Gastroenterological Surgery, EarlyView.
This prospective randomized trial evaluated whether prehabilitation, exercise and nutrition intervention, enhance skeletal muscle mass during neoadjuvant chemotherapy in older patients with esophageal cancer undergoing esophagectomy. We also investigated whether exercise alone was sufficient to increase skeletal muscle mass, and whether nutritional ...
Keijiro Sugimura, Takashi Kanemura, Tomohira Takeoka, Takahito Sugase, Norihiro Matsuura, Kazuyoshi Yamamoto, Masahiko Yano, Hiroshi Miyata   +7 more
wiley   +1 more source

Operative outcomes following neoadjuvant chemotherapy and stereotactic body radiation therapy (sbrt) for borderline resectable and locally advanced pancreatic cancer [PDF]

, 2019
Sara Zakem, Arndt-Christian Mueller, Cheryl Meguid, Robert J. Torphy, Bhavana V. Chapman, Tracey E. Schefter, Alexis D. Leal, S L Davis, Siew Hong Leong, Christopher H. Lieu, Wells A. Messersmith, W. Thomas Purcell, Steven A. Ahrendt, Martin M. McCarter, Schulick, Marco Del Chiaro, Karyn A. Goodman   +16 more
openalex   +1 more source

Pathologic assessment of the treatment effects of neoadjuvant therapy in patients with pancreatic cancer

, 2021
Yuko Nakano‐Narusawa, Juanjuan Ye, Yoko Matsuda   +2 more
openalex   +2 more sources

Laparoscopic Colorectal Surgery in the Era of Robotics: Evolution, Eclipse, or Equilibrium?

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Minimally invasive colorectal surgery has undergone a remarkable transformation over the past three decades. Laparoscopy, once viewed with skepticism, is now firmly established as a standard approach, supported by robust randomized trials demonstrating oncologic safety and improved recovery compared to open surgery.
Amanjeet Singh, Archit Gupta, Azhar Perwaiz, Adarsh Chaudhary   +3 more
wiley   +1 more source