Results 131 to 140 of about 2,703,409 (308)

Neoadjuvant Therapy [PDF]

open access: yesJAMA Oncology, 2015
Howard (Jack) West, Jill Jin
openaire   +1 more source

Neoadjuvant therapy for ovarian cancer

open access: yesChinese Clinical Oncology, 2018
Ovarian cancer (OC) is a common oncological disease, which affects approximately 1.5% of women and holds the first position in the structure of gynecological cancer mortality.
openaire   +2 more sources

Impact of Postoperative Infectious Complications on Long‐Term Survival After Curative Resection for Colorectal Cancer: A Multicenter Study in the Minimally Invasive Era

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Postoperative infectious complications (PICs) have been associated with poor long‐term outcomes after colorectal cancer surgery, but evidence in the modern minimally invasive era remains limited. In this multicenter cohort of 5377 patients undergoing curative resection, PICs were independently associated with worse overall survival and relapse‐free ...
Takehito Yamamoto   +7 more
wiley   +1 more source

Interaction Between Operator and Assistant Certification Is Associated With Local Recurrence After Laparoscopic Rectal Cancer Surgery: An Ancillary Analysis of the EnSSURE Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
A significant synergistic interaction between operator and assistant certification was associated with a lower risk of local recurrence after laparoscopic rectal cancer surgery. Patients treated by both ESSQS‐qualified operators and assistants had the lowest risk of local recurrence, whereas a single qualification alone was not associated with a ...
Yusuke Sakimura   +114 more
wiley   +1 more source

Prognostic Impact of Circumferential Resection Margin in Minimally Invasive Surgery for Locally Advanced Rectal Cancer: A Multicenter Prospective Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This multicenter prospective study provides the first Japanese evidence that circumferential resection margin positivity after minimally invasive surgery is associated with poorer long‐term outcomes in locally advanced rectal cancer. As the cohort predominantly included patients treated with upfront surgery, these findings provide important evidence to
Atsushi Hamabe   +19 more
wiley   +1 more source

Achievement of the Ideal Outcome After Pancreatectomy for Pancreatic Ductal Adenocarcinoma Is Associated With Earlier Initiation and Higher Completion Rates of Adjuvant Chemotherapy and Improved Long‐Term Survival

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background The Ideal Outcome is a composite quality indicator reflecting optimal postoperative course after pancreatic surgery. This study aimed to clarify the prognostic significance of achieving the Ideal Outcome and its influence on the initiation and completion of adjuvant chemotherapy.
Ryosuke Fukushima   +9 more
wiley   +1 more source

Biliary microbiome in pancreatic cancer: alterations with neoadjuvant therapy

open access: yes, 2019
Background: Neoadjuvant therapy for pancreatic cancer is being employed more commonly. Most of these patients undergo biliary stenting which results in bacterial colonization and more surgical site infections (SSIs). However, the influence of neoadjuvant
Hoffman, John P.   +4 more
core   +1 more source

CD86‐Positive Mature Tertiary Lymphoid Structures Are Associated With CD8+ T‐Cell Infiltration and Favorable Clinical Outcomes in Pancreatic Ductal Adenocarcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
CD86‐positive mature tertiary lymphoid structures were associated with increased intratumoral CD8+ T‐cell infiltration, a higher proportion of Granzyme B‐expressing CD8+ T cells in an exploratory analysis, and favorable clinical outcomes in pancreatic ductal adenocarcinoma.
Takaomi Seki   +10 more
wiley   +1 more source

Prognostic value of tumor deposits and their different response to neoadjuvant therapy in locally advanced rectal cancer.

open access: yesPLoS ONE
BackgroundTumor deposits (TDs) may have a worse prognosis in rectal cancer, but their significance in the neoadjuvant era is less certain. Post-treatment TDs might even be a sign of tumor response.
Di Zhou   +7 more
doaj   +1 more source

Limited benefits of neoadjuvant therapy on R0 resection rate and overall survival in patients with resectable or locally advanced PDAC in randomized controlled trials

open access: yesFrontiers in Medicine
A review of randomized controlled trials (RCTs) was conducted to assess the efficacy of neoadjuvant therapy for pancreatic ductal adenocarcinoma (PDAC).
Hao Liang, Ya-Kun Wu
doaj   +1 more source

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