Results 141 to 150 of about 144,610 (311)

Prevalence of MSI‐H/dMMR Colorectal Cancer in Japan: Data From the Clinical Study Group of the University of Osaka‐Colorectal Registry

Annals of Gastroenterological Surgery, EarlyView.
Using a multicenter Japanese colorectal cancer cohort from 25 institutions, we analyzed 1464 patients across all disease stages and tumor locations to determine the prevalence and clinicopathological features of MSI‐H/dMMR colorectal cancer. MSI‐H/dMMR tumors accounted for 9.4% of cases overall, were present in 22% of right‐sided colon cancers, and ...
Yoshihiro Morimoto, Mamoru Uemura, Yoshinori Kagawa, Hidekazu Takahashi, Masayuki Hiraki, Yozo Suzuki, Shinichi Yoshioka, Mitsuyoshi Tei, Shu Okamura, Yukako Mokutani, Atsushi Naito, Shinji Tokuyama, Takamichi Komori, Akinobu Yasuyama, Genta Sawada, Yujiro Fujie, Shinya Yamashita, Naotsugu Haraguchi, Yusuke Matsuura, Chu Matsuda, Yoshinao Chinen, Tatsushi Shingai, Katsuki Danno, Nobuo Tanaka, Kazuya Sakata, Kohei Murata, Yuichiro Doki, Hidetoshi Eguchi   +27 more
wiley   +1 more source

Limited benefits of neoadjuvant therapy on R0 resection rate and overall survival in patients with resectable or locally advanced PDAC in randomized controlled trials

Frontiers in Medicine
A review of randomized controlled trials (RCTs) was conducted to assess the efficacy of neoadjuvant therapy for pancreatic ductal adenocarcinoma (PDAC).
Hao Liang, Ya-Kun Wu
doaj   +1 more source

Neoadjuvant-Based Triple Therapy for Hepatocellular Carcinoma with Type I/II Portal Vein Tumor Thrombosis

Guimin Hou,1,* Feng Zhang,1,* Xielin Feng,1 Yan Chen,2 Jinliang Zhang,1 Haiqing Wang1 1Department of Hepatopancreatobiliary Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital and Institute, Affiliated Cancer Hospital of
Zhang F, Zhang J, Feng X, Chen Y, Wang H, Hou G   +5 more
core  

Sex‐Based Body Composition Changes in Patients With Rectal Cancer Undergoing Preoperative Chemoradiotherapy: A Prospective Observational Study

Annals of Gastroenterological Surgery, EarlyView.
This prospective study observed that preoperative chemoradiotherapy for rectal cancer was associated with reductions in body fat and grip strength, which appeared to be more pronounced in female patients. These findings suggest that sex‐sensitive nutritional and exercise support may be beneficial to help maintain muscle mass and physical function ...
Shinya Abe, Hiroaki Nozawa, Kentaro Abe, Yumi Yokota, Shunsuke Hori, Yusuke Taguchi, Mitsutaka Yakabe, Kazuhito Sasaki, Sumito Ogawa, Soichiro Ishihara   +9 more
wiley   +1 more source

Prognostic value of tumor deposits and their different response to neoadjuvant therapy in locally advanced rectal cancer.

PLoS ONE
BackgroundTumor deposits (TDs) may have a worse prognosis in rectal cancer, but their significance in the neoadjuvant era is less certain. Post-treatment TDs might even be a sign of tumor response.
Di Zhou, Junjun Zhou, Bin Hu, Yinjue Yu, Yuhai Bian, Cuiping Yang, Yongrui Bai, Haiyan Chen   +7 more
doaj   +1 more source

Percentage methylation frequency and neoadjuvant therapy.

, 2012
The % methylation in tumors with neoadjuvant therapy (n = 9−2 luminal; 4 basal-like and 3 triple-negative cases) and without (n = 53; Mann-Whitney). There were 3 cases for which neoadjuvant therapy data was not available.
Bernard Kwabi-Addo (45546), Atsushi Terunuma (160968), Tiffany H. Dorsey (160966), Songping Wang (160963), Rick A. Kittles (160971), Stefan Ambs (37080)   +5 more
core   +1 more source

Innovations in Gastric Cancer Surgery During Early Minimally Invasive Era and Future Perspectives

Annals of Gastroenterological Surgery, EarlyView.
With continuing revelations in tumor biology and the emergence of artificial intelligence, new horizons for surgical innovation are opening. At the center of this transformative journey stands the innovative surgeon, driven by passion, guided by data, and steadfast in the commitment to patient safety and quality of life.
Reut El‐On, Young‐Woo Kim
wiley   +1 more source

Short-term benefit of neoadjuvant hormone therapy in patients with localized high-risk or limited progressive prostate cancer

, 2019
Bing-Lei Ma,1,2,* Lin Yao,1,2,* Yu Fan,1,2 Yu Wang,1,2 Yi-Sen Meng,1,2 Qian Zhang,1,2 Zhi-Song He,1,2 Jie Jin,1,2 Li-Qun Zhou1,21Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, Beijing, People’s ...
Yao L, Fan Y, He ZS, Zhou LQ, Wang Y, Jin J, Zhang Q, Ma BL, Meng YS   +8 more
core  

Predicting the Efficacy of Adjuvant Chemotherapy Using Immuno‐Nutritional and Inflammatory Markers in Elderly Patients With Stage III Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to determine whether immuno‐nutritional and inflammatory markers could serve as predictors of the outcomes of postoperative adjuvant chemotherapy for stage III colorectal cancer in elderly patients. Postoperative lymphocyte‐to‐monocyte ratio and postoperative C‐reactive protein‐to‐albumin ratio accurately predicted the efficacy of ...
Tomoya Tago, Yasuyuki Takamizawa, Takeharu Kato, Hiroshi Nagata, Konosuke Moritani, Shunsuke Tsukamoto, Yukihide Kanemitsu   +6 more
wiley   +1 more source

Does loss of ARID1A expression affect neoadjuvant chemoradiotherapy response in rectal carcinomas?

Polish Journal of Pathology
This study evaluated the difference of ARID1A protein immunoexpression between responders and non-responders to neoadjuvant chemoradiotherapy in locally advanced rectal cancers.
Nagehan O. Barisik, Sibel Sensu, Sevinc H. Keser, Yesim S. Gurbuz, Ozgul Ozdemir, Ramazan O. Yuceer, AylinE. Gul, Nusret Erdogan   +7 more
doaj   +1 more source