Results 111 to 120 of about 144,610 (311)

Neoadjuvant therapy for gastroesophageal adenocarcinoma

World Journal of Clinical Oncology, 2016
Gastric and esophageal adenocarcinomas are one of the main causes of cancer-related death worldwide. While the incidence of gastric adenocarcinoma is decreasing, the incidence of gastroesophageal junction adenocarcinoma is rising rapidly in Western countries.
Emmanuelle, Samalin, Marc, Ychou
openaire   +2 more sources

The Predictors of Complete Pathologic Response in Rectal Cancer during the Total Neoadjuvant Therapy Era: A Systematic Review

, 2023
The modern rectal cancer treatment paradigm offers additional opportunities for organ preservation, most notably via total neoadjuvant therapy (TNT) and consideration for a watch-and-wait (WW) surveillance-only approach.
Ira L. Leeds, Haddon J. Pantel, Kurt S. Schultz, Emily Flom   +3 more
core   +1 more source

Lymph Node Metastasis Pattern and Influencing Factors in Esophageal Squamous Cell Carcinoma

AGING MEDICINE, EarlyView.
Among 388 patients with esophageal squamous cell carcinoma who underwent curative resection, 144 (37.1%) developed lymph node metastasis. Upper thoracic tumors mainly involved upper mediastinal and upper right paratracheal nodes, whereas lower thoracic tumors more often involved paracardial and abdominal nodes.
Yuheng Wang, Qingqing Ding, Lei Xue, Jinhua Luo   +3 more
wiley   +1 more source

Total Neoadjuvant Therapy With Short-Course Radiation: US Experience of a Neoadjuvant Rectal Cancer Therapy

, 2022
BACKGROUND: Short-course radiation followed by chemotherapy as total neoadjuvant therapy has been investigated primarily in Europe and Australia with increasing global acceptance.
Bauer, Philip, Trikalinos, Nikolaos A, Silviera, Matthew L, Roy, Amit, Makhdoom, Bilal A, Kim, Hyun, Pedersen, Katrina S, Chapman, William C, Hunt, Steven R, Mutch, Matthew G, Glasgow, Sean C, Parikh, Parag J   +11 more
core   +1 more source

Validity of upfront surgery for patients with unsuspected lymph node metastasis in esophageal cancer: a propensity scoring matching study

Journal of Cardiothoracic Surgery, 2018
Background Although neoadjuvant therapy followed by esophagectomy is well-established as being superior to upfront esophagectomy when locoregional lymph node (LN) metastasis is present in esophageal cancer, upfront esophagectomy without neoadjuvant ...
Jae Kil Park, Jae Jun Kim, Seok Whan Moon, Deog Gon Cho   +3 more
doaj   +1 more source

A Re-Examination of Neoadjuvant Therapy for Thymic Tumors: A Long and Winding Road

For most patients with advanced thymic epithelial tumors (TETs), a complete resection is a strong indicator of a better prognosis. But sometimes, primary surgery is unsatisfactory, and preoperative therapy is needed to facilitate complete resection ...
Zhitao Gu, Xiuxiu Hao, Fenghao Yu, Xuefei Zhang, Ning Xu, Changlu Wang, Yizhuo Zhao, Teng Mao, Wentao Fang   +8 more
core   +1 more source

Neoadjuvant Therapy in Pancreatic Cancer: Review Article

, 2015
Context Pancreatic cancer is still associated with a high mortality and morbidity for affected patients. To this date the role of neoadjuvant therapy in the standard treatment of pancreatic cancer remains elusive.
Deichmann, Steffen, Pross, Moritz, Jung, Carlo, Honselmann, Kim C, Keck, Tobias, Bausch, Dirk, Wellner, Ulrich F   +6 more
core   +1 more source

Impact of Abdominoperineal Resection on Postoperative Male Sexual Function After Minimally Invasive Rectal Cancer Surgery: A Subgroup Analysis From the LANDMARC Study

Annals of Gastroenterological Surgery, EarlyView.
Abdominoperineal resection (APR) after minimally invasive rectal cancer surgery was associated with significantly higher rates of erectile and early ejaculatory dysfunction compared with anal‐sparing surgery. Although ejaculatory function showed partial recovery over time, erectile dysfunction persisted up to 12 months postoperatively.
Taiki Kajiwara, Shinobu Ohnuma, Michiaki Unno, Masakatsu Numata, Tomohiro Yamaguchi, Koya Hida, Tomonori Akagi, Suguru Hasegawa, Akio Shiomi, Ryo Inada, Manabu Shiozawa, Keisuke Kazama, Masanori Hotchi, Masahiko Watanabe, Takeshi Naitoh   +14 more
wiley   +1 more source

Cost-Effectiveness of Perioperative Immune Checkpoint Therapy for NSCLC in Japan, the United States, and Brazil

JTO Clinical and Research Reports
Introduction: Immune checkpoint inhibitors (ICIs) are increasingly being used to treat lung cancer perioperatively. Although ICI use has led to long-term improvements in patient outcomes, its high costs have increased medical expenses.
Masahiro Fujioka, MD, Toshihiko Aranishi, PhD, Takehito Shukuya, MD, PhD, Luiz Araujo, MD, PhD, Dwight Owen, MD, MS, Tina Sowers, FACHE, Yukina Shirai, MD, PhD, David P. Carbone, MD, PhD, FASCO, Kazuhisa Takahashi, MD, PhD   +8 more
doaj   +1 more source

Impact of Prophylactic Cefepime on Surgical Site Infection and Severe Morbidity in Patients Who Underwent Pancreaticoduodenectomy With Preoperative Biliary Drainage

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Although prophylactic broad‐spectrum antibiotics can reduce postoperative complications after pancreaticoduodenectomy (PD), the optimal regimen remains uncertain. This study evaluated the impact of prophylactic cefepime (CFPM) on surgical site infection (SSI) and severe morbidity after PD with preoperative biliary drainage.
Genki Watanabe, Akihiro Murata, Yu Kasamatsu, Atsushi Ishihara, Daisuke Nagashima, Tetsuzo Tashima, Shintaro Kodai, Akishige Kanazawa, Sadatoshi Shimizu   +8 more
wiley   +1 more source