Results 161 to 170 of about 4,593,278 (410)

Induction chemotherapy followed by neoadjuvant chemoradiotherapy and surgery in locally advanced rectal cancer: preliminary results of a phase II study [PDF]

, 2018
PURPOSE: To report preliminary results of induction chemotherapy (IC) followed by neoadjuvant chemoradiotherapy (CRT) and surgery in locally advanced rectal cancer (LARC) patients.MATERIALS AND METHODS: This is the preliminary evaluation of a phase II ...
Benevento, Ilaria, Bulzonetti, Nadia, Cortesi, Enrico, D'Ambrosio, Giancarlo, De Felice, Francesca, Iafrate, Franco, Iannitti, Marcella, Mancini, Marialaura, Marampon, Francesco, Marzo, Marco, Musio, Daniela, Tombolini, Vincenzo, Urbano, Federica   +12 more
core   +1 more source

Prognostic Impact of Bone Mineral Density Reduction During Neoadjuvant Chemotherapy (NAC) in Patients Undergoing NAC Followed by Esophagectomy for Esophageal Cancer

Annals of Gastroenterological Surgery, EarlyView.
The association between BMD reduction during NAC and the worse prognosis remains unknown, although NAC followed by esophagectomy is a standard treatment for advanced ESCC. This study appeared that BMD massive reduction was an independent prognostic factor on OS (HR, 3.30; 95% confidence interval [CI], 1.69–6.55) and RFS (HR, 2.08; 95% CI, 1.19–3.63 ...
Kazuhide Sato, Keita Takahashi, Yoshitaka Ishikawa, Naoko Fukushima, Takahiro Masuda, Takanori Kurogochi, Masami Yuda, Akira Matsumoto, Kazuto Tsuboi, Yuichiro Tanishima, Fumiaki Yano, Ken Eto   +11 more
wiley   +1 more source

Results of neoadjuvant chemotherapy and radiation therapy in the breast-conserving treatment of 250 patients with all stages of infiltrative breast cancer [PDF]

, 1990
C Jacquillat, Marise Weil, F Baillet, Christian Borel, G Auclerc, M. A. De Maublanc, Martin Housset, Geneviève Forget, L Thill, Claude Soubrane, David Khayat   +10 more
openalex   +1 more source

Survival Outcomes of Esophageal Squamous Cell Carcinoma Patients Who Underwent Salvage Esophagectomy: A Literature Review and Results From Two High‐Volume Centers

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to investigate survival outcomes, the efficacy of lymph node (LN) dissection, and recurrence patterns in 69 patients who underwent R0 salvage surgery for esophageal squamous cell carcinoma. Of note, abdominal LN metastases had a negative impact on survival in our series.
Kotaro Sugawara, Koichi Yagi, Takashi Fukuda, Shoh Yajima, Daiji Oka, Yoshiyuki Miwa, Shuichiro Oya, Asami Okamoto, Raito Asaoka, Yoshifumi Baba   +9 more
wiley   +1 more source

Monitoring of neoadjuvant chemotherapy through time domain diffuse optics: Breast tissue composition changes and collagen discriminative potential [PDF]

arXiv
The purpose of this clinical study is to test broad spectral range (635-1060 nm) time domain diffuse optical spectroscopy in monitoring the response of breast cancer patients to neoadjuvant chemotherapy (NAC). The broadband operation allows us to fully analyze tissue composition in terms of hemoglobin, water, lipids and collagen concentration, which ...
arxiv  

Personalized circulating tumor DNA analysis to detect residual disease after neoadjuvant therapy in breast cancer

Science Translational Medicine, 2019
A robust personalized ctDNA test, TARDIS, achieves high accuracy for residual disease after completion of neoadjuvant therapy. Early detection, no time travel needed Analysis of tumor DNA shed into a patient’s circulation can provide a noninvasive means ...
B. R. McDonald, T. Contente-Cuomo, S. Sammut, Ahuva Odenheimer-Bergman, Brenda J Ernst, N. Perdigones, S. Chin, M. Farooq, Rosa Mejia, P. Cronin, K. Anderson, H. Kosiorek, D. Northfelt, A. McCullough, B. Patel, J. Weitzel, T. Slavin, C. Caldas, B. Pockaj, M. Murtaza   +19 more
semanticscholar   +1 more source

Essential Update 2023/2024: Multidisciplinary Treatment for Invasive Intraductal Papillary Mucinous Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Invasive intraductal papillary mucinous carcinoma (IPMC) has a high malignant potential, with surgical resection being the only potentially curative treatment. However, even after surgical resection, recurrence occurs frequently and the prognosis is poor once recurrence develops. While retrospective studies aiming to achieve long‐term survival
Seiko Hirono
wiley   +1 more source

Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial

Nature Network Boston, 2022
I. Reijers, A. Menzies, A. V. Van Akkooi, J. Versluis, N. V. D. van den Heuvel, R. Saw, T. Pennington, E. Kapiteijn, A. V. D. van der Veldt, K. Suijkerbuijk, G. Hospers, E. Rozeman, W. Klop, W. V. van Houdt, K. Sikorska, J. A. van der Hage, D. Grünhagen, M. Wouters, A. Witkamp, C. Zuur, J. Lijnsvelt, A. Torres Acosta, L. Grijpink-Ongering, Maria Gonzalez, K. Jóźwiak, C. Bierman, K. Shannon, S. Ch’ng, A. Colebatch, A. Spillane, J. Haanen, R. Rawson, B. A. Van de Wiel, L. V. van de Poll-Franse, R. Scolyer, A. Boekhout, G. Long, C. Blank   +37 more
semanticscholar   +1 more source

Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Urothelial Bladder Carcinoma (PURE-01): An Open-Label, Single-Arm, Phase II Study.

Journal of Clinical Oncology, 2018
PURPOSE To determine the activity of pembrolizumab as neoadjuvant immunotherapy before radical cystectomy (RC) for muscle-invasive bladder carcinoma (MIBC) for which standard cisplatin-based chemotherapy is poorly used. PATIENTS AND METHODS In the PURE-
A. Necchi, A. Anichini, D. Raggi, A. Briganti, S. Massa, R. Lucianò, M. Colecchia, P. Giannatempo, R. Mortarini, M. Bianchi, E. Faré, Francesco Monopoli, R. Colombo, A. Gallina, A. Salonia, A. Messina, Siraj M. Ali, R. Madison, J. Ross, Jon H. Chung, R. Salvioni, L. Mariani, F. Montorsi   +22 more
semanticscholar   +1 more source

Preoperative Versus Postoperative Chemotherapy With CAPOX Plus Bevacizumab for Resectable Colorectal Liver Metastases: A Randomized Phase II Trial (HiSCO‐01)

Annals of Gastroenterological Surgery, EarlyView.
Our aim was to compare the outcomes of preoperative chemotherapy with postoperative chemotherapy in patients with resectable colorectal liver metastases treated with CAPOX‐Bev. We demonstrated that both preoperative and postoperative CAPOX‐Bev were safely administered, and preoperative chemotherapy showed a numerically higher treatment compliance rate ...
Yuji Takakura, Katsunori Shinozaki, Satoshi Ikeda, Hiroyuki Egi, Yuzo Hirata, Manabu Shimomura, Takafumi Oshiro, Takao Hinoi, Daisuke Sumitani, Masahiro Nakahara, Masanori Yoshimitsu, Naruhiko Honmyo, Tsuyoshi Kobayashi, Junko Tanaka, Hideki Ohdan, on behalf of the Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)   +15 more
wiley   +1 more source