Results 11 to 20 of about 2,507,641 (307)

Neoadjuvant Therapy and the Evolving Management of Resectable Advanced Melanoma. [PDF]

Cancers (Basel)
Melanoma has long represented a unique challenge in oncology. In its early stages, it can often be cured with surgery alone, resulting in excellent survival outcomes.
Papadopoulos N, Del Vecchio M, Spagnoletti A, Pigozzo J, Piccin L, Minisini A, Pravisano F, Roccuzzo G, Fava P, Cimminiello C.   +9 more
europepmc   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta-analysis of publicly available transcriptomic RNA-seq datasets. [PDF]

Mol Oncol
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Stanojevic A, Stroggilos R, Marinkovic M, Djuric A, Stojanovic-Rundic S, Jankovic R, Castellvi-Bel S, Fijneman RJA, Vlahou A, Zoidakis J, Cavic M.   +10 more
europepmc   +2 more sources

Predicting Response to Neoadjuvant Therapy in Oesophageal Adenocarcinoma [PDF]

, 2022
(1) Background: Oesophageal cancers are often late-presenting and have a poor 5-year survival rate. The standard treatment of oesophageal adenocarcinomas involves neoadjuvant chemotherapy with or without radiotherapy followed by surgery.
Read, Matthew, Jelske M. de Jong, de Jong, Jelske M., Jiang, William, Matthew Read, William Jiang, van Hillegersberg, Richard, Richard van Hillegersberg   +7 more
core   +1 more source

Androgen deprivation therapy plus apalutamide as neoadjuvant therapy prior radical prostatectomy for patients with unresectable prostate cancer

Frontiers in Pharmacology, 2023
Whether neoadjuvant therapy confers a survival benefit in advanced prostate cancer (PCa) remains uncertain. The primary endpoints of previous retrospective and phase II clinical studies that used neoadjuvant therapy, including androgen deprivation ...
Yongbao Wei, Yongbao Wei, Ruochen Zhang, Ruochen Zhang, Dewen Zhong, Zhensheng Chen, Gen Chen, Minggen Yang, Le Lin, Le Lin, Tao Li, Tao Li, Liefu Ye, Liefu Ye, Lili Chen, Lili Chen, Qingguo Zhu, Qingguo Zhu   +17 more
doaj   +1 more source

The Therapeutic Effectiveness of Neoadjuvant Trastuzumab Plus Chemotherapy for HER2-Positive Breast Cancer Can Be Predicted by Tumor-Infiltrating Lymphocytes and PD-L1 Expression

Frontiers in Oncology, 2022
IntroductionNeoadjuvant trastuzumab plus chemotherapy may affect programmed death-ligand 1 (PD-L1) expression and tumor-infiltrating lymphocytes (TILs) in HER2-positive breast cancer.
Mao Shang, Mao Shang, Yajing Chi, Jianbo Zhang, Jin Chang, Hui Yang, Sha Yin, Qiaorui Tan, Xiaochu Man, Huihui Li   +9 more
doaj   +1 more source

Case report: Major pathologic response induced by neoadjuvant treatment using BRAF and MEK inhibitors in a patient with stage IIIA lung adenocarcinoma harboring BRAF V600E-mutation

Frontiers in Oncology, 2022
Targeted therapy has achieved great success in advanced non-small lung cancer (NSCLC) with driver genes, and neoadjuvant-targeted therapy is increasingly being investigated.
Chaoyuan Liu, Min Lu, Yang Yang, Xiang Wang, Fang Ma, Xianling Liu   +5 more
doaj   +1 more source

Clinical Outcome of Laparoscopic Colorectal Resection after Neoadjuvant Chemo-Radiotherapy for Colorectal Carcinoma [PDF]

Zagazig University Medical Journal, 2021
:Introduction :Neoadjuvant chemo-radiotherapy has the advantages of decrease local recurrence rate , deceasing toxicity , down_staging the tumor and minimize rate of mobidity .Methods: Patients were divided into 2 groups in accordance type of ...
said negm, Hazem nour, Ahmed mohamed, Mohamed zaitoun   +3 more
doaj   +1 more source

An open, observational, three-arm clinical study of 2–3 cycles of treatment as neoadjuvant therapy in operable locally advanced non-small cell lung cancer: An interim analysis

Frontiers in Immunology, 2022
BackgroundAn open, observational, three-arm clinical study aimed at investigating the efficacy of different neoadjuvant therapies (neoadjuvant immunotherapy with(out) chemotherapy, neoadjuvant chemotherapy, and neoadjuvant targeted therapy) in operable ...
Linping Gu, Xue Wang, Yile Sun, Yunhua Xu, Xiaomin Niu, Ruiying Zhao, Yaxian Yao, Hong Jian, Yuchen Han, Jinwang Wei, Zhiwei Chen, Shun Lu   +11 more
doaj   +1 more source

Breast cancer: Monitoring response to neoadjuvant chemotherapy using Tc-99m sestamibi scintimammography [PDF]

, 2003
Background: Aim of the study was to assess the value of scintimammography using Tc-99m sestamibi in the evaluation of tumor response to neoadjuvant chemotherapy.
Sommer, H., Keßler, M., Tiling, R., Brinkbäumer, K., Hahn, K., Untch, M., Linke, R.   +6 more
core   +1 more source

Trimodal Therapy in Esophageal Squamous Cell Carcinoma: Role of Adjuvant Therapy Following Neoadjuvant Chemoradiation and Surgery

, 2022
SIMPLE SUMMARY: In this work, we aimed to explore the effectiveness of adjuvant therapy after trimodal therapy (neoadjuvant chemoradiotherapy and esophagectomy) in patients with thoracic esophageal squamous cell carcinoma (ESCC).
Fang, Pinhao, Shang, Qixin, Xiao, Xin, Hanlu Zhang, Pinhao Fang, Yong Yuan, Luan, Siyuan, Xin Xiao, Xiaokun Li, Siyuan Luan, Yang, Yushang, Zhou, Jianfeng, Yushang Yang, Yuan, Yong, Jianfeng Zhou, Qixin Shang, Li, Xiaokun, Zhang, Hanlu   +17 more
core   +1 more source