Results 11 to 20 of about 2,703,409 (308)

Neoadjuvant therapy for oesophagogastric cancer

British Journal of Surgery, 2004
Abstract Background The prognosis after surgery for oesophagogastric cancer remains poor. Methods This review clarifies current indications for neoadjuvant therapy for oesophageal and gastric cancer.
F, Lordick, H J, Stein, C, Peschel, J R, Siewert   +3 more
openaire   +3 more sources

Predicting Response to Neoadjuvant Therapy in Oesophageal Adenocarcinoma [PDF]

, 2022
(1) Background: Oesophageal cancers are often late-presenting and have a poor 5-year survival rate. The standard treatment of oesophageal adenocarcinomas involves neoadjuvant chemotherapy with or without radiotherapy followed by surgery.
Read, Matthew, Jelske M. de Jong, de Jong, Jelske M., Jiang, William, Matthew Read, William Jiang, van Hillegersberg, Richard, Richard van Hillegersberg, MS CGO, Cancer   +9 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta-analysis of publicly available transcriptomic RNA-seq datasets. [PDF]

Mol Oncol
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Stanojevic A, Stroggilos R, Marinkovic M, Djuric A, Stojanovic-Rundic S, Jankovic R, Castellvi-Bel S, Fijneman RJA, Vlahou A, Zoidakis J, Cavic M.   +10 more
europepmc   +2 more sources

Case report: Major pathologic response induced by neoadjuvant treatment using BRAF and MEK inhibitors in a patient with stage IIIA lung adenocarcinoma harboring BRAF V600E-mutation

Frontiers in Oncology, 2022
Targeted therapy has achieved great success in advanced non-small lung cancer (NSCLC) with driver genes, and neoadjuvant-targeted therapy is increasingly being investigated.
Chaoyuan Liu, Min Lu, Yang Yang, Xiang Wang, Fang Ma, Xianling Liu   +5 more
doaj   +1 more source

Surgical Considerations for Neoadjuvant Therapy for Pancreatic Adenocarcinoma

, 2023
Pancreatic ductal adenocarcinoma (PDAC) is a challenging disease process with a 5-year survival rate of only 11%. Neoadjuvant therapy in patients with localized pancreatic cancer has multiple theoretical benefits, including improved patient selection for
Anish J. Jain, Matthew H. G. Katz, Jessica E. Maxwell, Rebecca A. Snyder   +3 more
core   +1 more source

Clinical Outcome of Laparoscopic Colorectal Resection after Neoadjuvant Chemo-Radiotherapy for Colorectal Carcinoma [PDF]

Zagazig University Medical Journal, 2021
:Introduction :Neoadjuvant chemo-radiotherapy has the advantages of decrease local recurrence rate , deceasing toxicity , down_staging the tumor and minimize rate of mobidity .Methods: Patients were divided into 2 groups in accordance type of ...
said negm, Hazem nour, Ahmed mohamed, Mohamed zaitoun   +3 more
doaj   +1 more source

Trimodal Therapy in Esophageal Squamous Cell Carcinoma: Role of Adjuvant Therapy Following Neoadjuvant Chemoradiation and Surgery

, 2022
SIMPLE SUMMARY: In this work, we aimed to explore the effectiveness of adjuvant therapy after trimodal therapy (neoadjuvant chemoradiotherapy and esophagectomy) in patients with thoracic esophageal squamous cell carcinoma (ESCC).
Fang, Pinhao, Shang, Qixin, Xiao, Xin, Hanlu Zhang, Pinhao Fang, Yong Yuan, Luan, Siyuan, Xin Xiao, Xiaokun Li, Siyuan Luan, Yang, Yushang, Zhou, Jianfeng, Yushang Yang, Yuan, Yong, Jianfeng Zhou, Qixin Shang, Li, Xiaokun, Zhang, Hanlu   +17 more
core   +1 more source

An open, observational, three-arm clinical study of 2–3 cycles of treatment as neoadjuvant therapy in operable locally advanced non-small cell lung cancer: An interim analysis

Frontiers in Immunology, 2022
BackgroundAn open, observational, three-arm clinical study aimed at investigating the efficacy of different neoadjuvant therapies (neoadjuvant immunotherapy with(out) chemotherapy, neoadjuvant chemotherapy, and neoadjuvant targeted therapy) in operable ...
Linping Gu, Xue Wang, Yile Sun, Yunhua Xu, Xiaomin Niu, Ruiying Zhao, Yaxian Yao, Hong Jian, Yuchen Han, Jinwang Wei, Zhiwei Chen, Shun Lu   +11 more
doaj   +1 more source

Breast cancer: Monitoring response to neoadjuvant chemotherapy using Tc-99m sestamibi scintimammography [PDF]

, 2003
Background: Aim of the study was to assess the value of scintimammography using Tc-99m sestamibi in the evaluation of tumor response to neoadjuvant chemotherapy.
Sommer, H., Keßler, M., Tiling, R., Brinkbäumer, K., Hahn, K., Untch, M., Linke, R.   +6 more
core   +1 more source

Administered neoadjuvant and adjuvant therapy regimens.

, 2022
All regimens, both neoadjuvant and adjuvant therapy, with the number of cycles used for both patients treated with neoadjuvant therapy and upfront surgery. NAT = Neoadjuvant therapy, US = Upfront surgery. (DOCX)
Harri Mustonen (641410), Hanna Seppänen (751179), Jaana Hagström (476954), Anna Maria Nurmi (12524924), Caj Haglund (476956)   +4 more
core   +1 more source